Evidence map›Paper›PMID 40501518›Full record

ArticleJournal of hematology2025

Efficacy of Short-Course High-Dose Oral Prednisolone in Rapid Platelet Recovery for Pediatric Acute Immune Thrombocytopenic Purpura: A Prospective Cohort Study.

Akshat Jhingan, Neha Goel, Amitabh Singh, Rani Gera, Nidhi Chopra, Sumit Mehndiratta, Monica Sharma

Abstract read
In one paragraph

Article in Journal of hematology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Akshat JhinganDepartment of Pediatrics, Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi 110029, India.ORCID https://orcid.org/0009-0003-5233-5718
Neha GoelDepartment of Pediatrics, Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi 110029, India.ORCID https://orcid.org/0000-0001-9575-0805
Amitabh SinghDepartment of Pediatrics, Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi 110029, India.ORCID https://orcid.org/0000-0002-4440-5339
Rani GeraDepartment of Pediatrics, Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi 110029, India.ORCID https://orcid.org/0000-0003-1497-4693
Nidhi ChopraDepartment of Pediatrics, Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi 110029, India.ORCID https://orcid.org/0000-0002-2499-7779
Sumit MehndirattaDepartment of Pediatrics, Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi 110029, India.ORCID https://orcid.org/0000-0002-0024-8773
Monica SharmaDepartment of Hematology, Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi 110029, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Standard management of acute immune thrombocytopenic purpura (ITP) remains debated, with some advocating observation for mild cases, while others recommend pharmacological intervention to accelerate platelet recovery in children with severe thrombocytopenia (TCP) (platelet count < 20,000/mm Methods: A total of 61 patients were enrolled, and their response to treatment was monitored at various intervals, including 48 h, 72 h, day 7, 1 month, and 3 months. Results: Results revealed a rapid platelet recovery in patients receiving high-dose PDN, with 83.6% of patients achieving platelet counts greater than 50,000/mm Conclusion: The study suggests that short-course high-dose PDN can be an effective first-line therapy for acute ITP. It promotes faster platelet recovery and reduces hospitalization time with minimal adverse effects.

Indexed as

CorticosteroidsImmune thrombocytopenic purpuraPrednisoloneThrombocytopenia

Identifiers

PMID40501518
PMCPMC12151098

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.