Evidence map›Paper›PMID 40501500›Full record

ArticleFood science & nutrition2025

Genetic Susceptibility to Causal Relationship Between Iron Metabolism Disorder Involving Immunocytes and Risk of Pneumonia and Sepsis.

Zhenchao Wu, Taikang Yao, Zhongyu Han, Zilu Wang, Beibei Liu, Ming Lu, Jiajia Zheng, Ning Shen

Abstract read
In one paragraph

Article in Food science & nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Zhenchao WuDepartment of Pulmonary and Critical Care Medicine Peking University Third Hospital Beijing People's Republic of China.ORCID https://orcid.org/0000-0002-1342-8773
Taikang YaoDepartment of Pulmonary and Critical Care Medicine Peking University Third Hospital Beijing People's Republic of China.ORCID https://orcid.org/0000-0002-0497-0595
Zhongyu HanDepartment of Laboratory Medicine Peking University Third Hospital Beijing People's Republic of China.
Zilu WangDepartment of Pulmonary and Critical Care Medicine Peking University Third Hospital Beijing People's Republic of China.ORCID https://orcid.org/0000-0003-3635-9843
Beibei LiuDepartment of Pulmonary and Critical Care Medicine Peking University Third Hospital Beijing People's Republic of China.
Ming LuCenter for Infectious Diseases Peking University Third Hospital Beijing People's Republic of China.
Jiajia ZhengDepartment of Laboratory Medicine Peking University Third Hospital Beijing People's Republic of China.
Ning ShenDepartment of Pulmonary and Critical Care Medicine Peking University Third Hospital Beijing People's Republic of China.ORCID https://orcid.org/0000-0003-2352-0677

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recent studies showed ferritin increase and hemoglobin decrease to COVID-19 severity and sepsis mortality. However, the potential relationship between iron metabolism disorders and susceptibility to pneumonia remains unclear. This study explores the association between iron metabolism disorder and susceptibility to bacterial pneumonia, viral pneumonia, and sepsis. GWAS data from the FinnGen and UK biobank is used for a two-sample Mendelian randomization (MR) analysis, followed by MR meta-analysis. Low serum iron levels were negatively associated with the risk of bacterial pneumonia (OR, 0.85;

Indexed as

immune celliron metabolismMendelian randomization analysispneumoniasepsis

Identifiers

PMID40501500
PMCPMC12152259

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.