Evidence map›Paper›PMID 40501493›Full record

ArticleDrug and alcohol dependence reports2025

Exploring the impact of a medication adherence intervention on recovery and mental health outcomes: A secondary analysis of the MAT-PLUS pilot RCT.

Kevin Wenzel, Julia Thomas, Jennifer Carrano, Jennifer Stidham, Marc Fishman

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Drug and alcohol dependence reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Kevin WenzelMaryland Treatment Centers, 3800 Frederick Ave, Baltimore, MD 21229, USA.
Julia ThomasMaryland Treatment Centers, 3800 Frederick Ave, Baltimore, MD 21229, USA.
Jennifer CarranoMaryland Treatment Centers, 3800 Frederick Ave, Baltimore, MD 21229, USA.
Jennifer StidhamMaryland Treatment Centers, 3800 Frederick Ave, Baltimore, MD 21229, USA.
Marc FishmanMaryland Treatment Centers, 3800 Frederick Ave, Baltimore, MD 21229, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Substance use disorders (SUDs) including opioid use disorder (OUD) and alcohol use disorder (AUD) contribute to significant morbidity and mortality in the United States. Pharmacotherapy treatment, including extended-release naltrexone (XR-NTX), is underutilized in large part due to poor treatment retention. The MAT-PLUS (Medication Adherence Therapy: Psychosocial Leverage Using a Significant other) intervention combines assertive outreach, significant other involvement, and low-barrier access to medicine to improve retention on XR-NTX, and has shown promising results in a pilot RCT.

Indexed as

Alcohol use disorderAssertive outreachExtended-release naltrexoneMedication adherenceOpioid use disorder

Identifiers

PMID40501493
PMCPMC12152343

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.