Evidence map›Paper›PMID 40501302›Full record

ArticleJournal of cosmetic dermatology2025

Clinical Efficacy of Composite Autologous Chylated Fat and Concentrated Growth Factors for Treating Postinjection Alopecia After Facial Fillers: A Single-Center Retrospective Study.

Shuo Tang, Guiwen Zhou, Qiang Fu, Minliang Chen

Abstract read
In one paragraph

Article in Journal of cosmetic dermatology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Trial
  2. Article
  3. Treatment for Filler-Induced Alopecia with Concentrated Growth Factors.Clinical, cosmetic and investigational dermatology · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Shuo TangSenior Department of Burns and Plastic Surgery, The Fourth Medical Center of Chinese PLA General Hospital, Beijing, , China.
Guiwen ZhouSenior Department of Burns and Plastic Surgery, The Fourth Medical Center of Chinese PLA General Hospital, Beijing, , China.
Qiang FuSenior Department of Burns and Plastic Surgery, The Fourth Medical Center of Chinese PLA General Hospital, Beijing, , China.
Minliang ChenSenior Department of Burns and Plastic Surgery, The Fourth Medical Center of Chinese PLA General Hospital, Beijing, , China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPostinjection alopecia is a rare but significant complication of facial fillers, likely caused by compromised microcirculation and follicular damage. Effective treatments are needed, but regenerative therapies specifically for this etiology lack systematic investigation.

objectiveThis study evaluated the efficacy and safety of combined autologous chylated fat (ACF) and concentrated growth factors (CGF) for treating acute alopecia following facial filler injection.

methodsIn this single-center, retrospective case series, nine female patients with acute alopecia (2-4 weeks post-HA filler) were treated between June 2021 and June 2024. Treatment involved three monthly subcutaneous injections of a 1:1 ACF and liquid CGF mixture (0.1 mL/cm

resultsAll nine patients completed the 6-month follow-up. Significant improvements (p < 0.001) were observed at 6 months compared to baseline: hair density increased from 32.7 ± 13.4 to 92.4 ± 23.4 hairs/cm

conclusionCombined ACF and CGF represent a promising and effective treatment for post-filler alopecia, offering a novel therapeutic option for early intervention and improved esthetic outcomes.

Indexed as

Adipose TissueAlopeciaCosmetic TechniquesDermal FillersIntercellular Signaling Peptides and ProteinsAdultFaceFemaleFollow-Up StudiesHairHumansHyaluronic AcidInjections, SubcutaneousMiddle AgedPatient SatisfactionRetrospective StudiesDermal FillersHyaluronic AcidIntercellular Signaling Peptides and Proteinsalopeciaautologous fatconcentrated growth factorsdermal fillersesthetic medicinefiller complications

Identifiers

PMID40501302
PMCPMC12159710

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.