ArticleJournal of cosmetic dermatology2025
Analysis of Skin Microbiome in Facial and Back Acne Patients Based on High-Throughput Sequencing.
Article in Journal of cosmetic dermatology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- The Role of Skin Microbiota in Facial Dermatoses and Related Factors: A Narrative Review.International journal of molecular sciences · 2025Review
- Effects of a Greek Yoghurt-based Complex on the Human Facial Skin Microbiome.In vivo (Athens, Greece)Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo study the composition and diversity of microorganisms in skin lesions of patients with facial acne and back acne, analyze the relationship between microorganisms and different parts of acne.
methodsA total of 30 facial acne patients, 30 back acne patients, and 30 healthy controls were included. Comprehensive data on demographics, skin conditions, and state of life were collected. Skin microbiota samples were obtained using standardized protocols, through high-throughput microbial sequencing and bioinformatics analysis, to assess microbiota diversity, composition, and function, as well as their correlations with skin characteristics.
resultsThe diversity of skin microbiota of back acne patients decreased significantly, and the abundance of p_actinomycetes and o_propionate bacteria increased significantly. They are closely related to glucose metabolism, which may lead to increased trans epidermal water loss, decreased skin moisture content, and increased skin oil content.
conclusionThe skin microbiota diversity of patients with back acne is low, and high-abundance bacteria are closely related to glucose metabolism, which may lead to the breakdown of the skin barrier and increased sebum secretion.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.