SynthesisEuropean journal of orthodontics2025
Effects of mouthwashes on the morphology, structure, and mechanical properties of orthodontic materials: a systematic review of randomized clinical studies.
Synthesis in European journal of orthodontics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Comparison of Clinical Effects of Essential Oil-Containing Mouthwash and Chlorhexidine Mouth Wash in Patients Undergoing Fixed Orthodontic Treatment - Three-Month Follow-up Randomized-Controlled Trial.Clinical and experimental dental research · 2026Trial
- Effect of Fluoride Exposure on the Mechanical Properties of NiTi Orthodontic Archwires: An In Vitro Study.Cureus · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTherapeutic mouthwashes are commonly used in dentistry to support mechanical plaque removal. Their interaction with orthodontic materials is increasingly studied due to potential effects on biocompatibility and biomechanics.
objectiveTo investigate in a systematic manner and evaluate the quality of the available evidence from randomized clinical trials regarding the effects of various mouthwashes on the morphology, structure, and mechanical properties of polymeric and metallic orthodontic materials. SEARCH
methodsComprehensive electronic and manual searches were conducted in seven databases from inception until August 2024. SELECTION CRITERIA: We analysed randomized controlled clinical studies that examined the impact of mouthwashes on the morphology, structure, and mechanical properties of both polymeric and metallic orthodontic materials. DATA COLLECTION AND ANALYSIS: Data eligibility, data extraction, and risk of bias (RoB-2 tool) were performed independently.
resultsTen studies were included, with most of them presenting some concerns in terms of bias. Chlorhexidine mouthrinse use did not affect the shear bond strength of polycarbonate brackets, the soldering alloys, as well as the stainless-steel bracket surfaces, but increased the roughness and friction of stainless-steel wires. The corrosion and mechanical properties of NiTi wires were not significantly affected by chlorhexidine. Rinsing with fluoride solutions increased surface roughness of NiTi wires, with more pronounced effects seen in acidulated fluoride solutions. While yield strength increased, no significant impacts on unloading force or modulus of elasticity was observed. Mouthwashes containing Salvadora persica did not significantly alter the surface topography of stainless-steel brackets and the roughness of stainless-steel archwires.
conclusionsThe evidence from randomized clinical trials suggests that chlorhexidine- and fluoride-containing mouthwashes may impact the structure and certain mechanical properties of stainless-steel and NiTi archwires. While study limitations exist, clinicians should be mindful of possible effects on orthodontic treatment. REGISTRATION: Open Science Framework: osf.io/hz6wk.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.