Evidence map›Paper›PMID 40501185›Full record

ReviewThe Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology2025

Etrasimod in Treatment of Ulcerative Colitis: A Comprehensive Review.

Osman Cagin Buldukoglu, Yusuf Erzin, Ayhan Hilmi Cekin, Silvio Danese

Abstract readReview
In one paragraph

Review in The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Prevalence of Latent and Active Tuberculosis Infection in Inflammatory Bowel Disease Patients Who Received Biological Treatment.The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Osman Cagin BuldukogluDepartment of Gastroenterology, University of Health Sciences, Antalya Training and Research Hospital, Antalya, Türkiye.
Yusuf ErzinDepartment of Gastroenterology, İstanbul Cerrahpaşa University Cerrahpaşa Faculty of Medicine, İstanbul, Türkiye.
Ayhan Hilmi CekinDepartment of Gastroenterology, University of Health Sciences, Antalya Training and Research Hospital, Antalya, Türkiye.
Silvio DaneseGastroenterology and Endoscopy Unit, IRCCS San Raffaele Hospital, Vita-Salute San Raffaele University Faculty of Medicine and Surgery, Milan, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ulcerative colitis (UC) is a chronic, inflammatory disease of the colon. The unpredictable, systemic, and debilitating nature of UC puts disease management and patient monitoring at a pivotal point. Despite substantial development in pharmacotherapies for UC in recent years, a significant proportion of patients either fail to respond to treatment or lose their response over the course of the disease. The backbone of disease management in UC is 5-aminosalicylic acid (5-ASA), but patients unresponsive to 5-ASA or with severe disease require advanced therapies including tumor necrosis factor-alpha inhibitors (TNFi), anti-integrins, anti-interleukins and small molecule therapy, Janus kinase (JAK) inhibitors, and S1PR modulators. This review will briefly overview the current state of medical therapeutic options in UC, with further detailing the molecular and clinical aspects of Etrasimod, a sphingosine-1-phosphate receptor (S1PR) modulator.

Indexed as

Colitis, UlcerativeSphingosine 1 Phosphate Receptor ModulatorsHumansMesalamineTreatment OutcomeMesalamineSphingosine 1 Phosphate Receptor ModulatorsEtrasimodtreatmentulcerative colitis

Identifiers

PMID40501185
PMCPMC12147382

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.