Trial reportBritish journal of health psychology2025
A randomized controlled trial of self-help cognitive behavioural therapy for depression in adults with pulmonary hypertension.
Trial report in British journal of health psychology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
7 citing papers in PubMed.
- A randomized controlled trial of self-help cognitive behavioural therapy for depression in adults with pulmonary hypertension.British journal of health psychology · 2025Trial
- Effect of Incident Pulmonary Arterial Hypertension on Risk of Newly-Diagnosed Mental Health Conditions.Pulmonary circulation · 2026Article
- Clinical Utility of the PHQ-2 and GAD-2 in Pulmonary Hypertension.Pulmonary circulation · 2026Article
- Mediating Effects of Fear of Movement and Self-Efficacy Between Illness Perception and Health-Related Quality of Life in Pulmonary Hypertension.Psychology research and behavior management · 2026Article
- Depression and Anxiety in Pulmonary Hypertension Associated With Congenital Heart Disease: Pathophysiology and Clinical Implications of the Heart-Brain Axis.Journal of the Saudi Heart Association · 2026Review
- The Role of Psychological Distress on Health-Related Quality of Life, Fatigue, and Pain in Adults With Pulmonary Hypertension.Pulmonary circulation · 2025Article
- Rehabilitation applications and progress in managing pulmonary hypertension.Frontiers in medicine · 2025Review
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesPulmonary hypertension (PH) is a progressive, life-reducing group of conditions associated with an elevated risk of depression. To meet this clinical need, we developed an unguided self-help intervention targeting depression in PH based on cognitive behavioural therapy (CBT) and tested its acceptability, feasibility, and effectiveness.
designA randomized controlled trial (RCT) design was utilized with a wait-list control group. Acceptability was assessed using content analysis.
methodsAdults self-reporting difficulties with depression were recruited from global Pulmonary Hypertension Associations. Participants were randomly assigned to the intervention (n = 33) or the wait-list control group (n = 35). Depression was the primary outcome; secondary outcomes included anxiety, health-related quality of life, pain self-efficacy, fatigue, and cognitions and behaviours associated with mood difficulties. Change from baseline to post-intervention (4 weeks) and follow-up (1 month later) was measured.
resultsWe found a significant reduction in depression and HRQoL in the intervention group compared with the control group, with medium effect sizes. No significant changes were observed in other outcomes (p > .05). Overall, 72% of individuals in the treatment arm scored above the clinical level of depression, compared with 28% at post-intervention and 36% at follow-up. The intervention was judged to be acceptable and feasible, with the main benefits including tools to support, increased motivation, and understanding of depression. No adverse events were reported. Change in cognitions and behaviours did not mediate the relationship between the intervention group and change in depression (p > .05).
conclusionsResults support the use of CBT for depression in PH and provide evidence for the delivery of self-help at scale via PHA-UK, the UK's leading charity for PH.
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