Evidence map›Paper›PMID 40501091›Full record

ArticleJournal of biosciences2025

ARP2/3 regulates cell surface dynamics of CeTOCA-1 in

Aadya Nageswaran, Promiti Mitra, Megha Rai, Diya Anand, Yogesh Pratap, Anup Padmanabhan

Abstract read
PubMed
In one paragraph

Article in Journal of biosciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. TOCA-2 regulates gonad development inmicroPublication biology · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Aadya NageswaranDepartment of Biology, Trivedi School of Biosciences, Ashoka University, Sonipat 131029, India.
Promiti Mitra
Megha Rai
Diya Anand
Yogesh Pratap
Anup Padmanabhan

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Polymerization of branched actin networks by the ARP2/3 complex plays a critical role in diverse cellular processes. ARP2/3 activity is tightly controlled by the upstream CDC-42 GTPase and effectors such as the Wiscott-Aldrich syndrome protein (N-WASP/Wiscott-Aldrich Syndrome Protein (WSP-1)) and members of the F-BAR containing transducer of CDC-42-dependent actin assembly (TOCA) protein family. While the mechanisms governing WASP/N-WASP (neural-WASP) functioning are well understood, the regulatory dynamics of TOCA proteins at the cell cortex remain poorly characterized. Here, using the

Indexed as

Actin-Related Protein 2-3 ComplexCaenorhabditis elegansCaenorhabditis elegans ProteinsZygoteActinsAnimalsCell Cycle ProteinsCell MembraneGTP-Binding ProteinsWiskott-Aldrich Syndrome ProteinActin-Related Protein 2-3 ComplexActinsCaenorhabditis elegans Proteinscdc-42 protein, C elegansCell Cycle ProteinsGTP-Binding ProteinsWiskott-Aldrich Syndrome Proteinwsp-1 protein, C elegans

Identifiers

PMID40501091

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.