ArticleClinical implant dentistry and related research2025
Marginal Bone Changes Around Tissue-Level Implants After Prosthesis Delivery: A Multicenter Prospective Study.
Article in Clinical implant dentistry and related research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05363306 (Influence of the Apico-coronal Position of Tissue-level Implants on Marginal Bone Stability), which is not on this map. Cited by 4 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Influence of the Apico-coronal Position of Tissue-level Implants on Marginal Bone Stability
Who cites it
4 citing papers in PubMed.
- Prosthetic Retention Mode and Peri-Implant Marginal Bone Level at a Minimum Five-Year Follow-Up After Maxillary Sinus Floor Elevation: A Retrospective Clustered Cohort Study.Journal of functional biomaterials · 2026Article
- Implant Surface Characteristics and Peri-Implant Outcomes: A Systematic Review of Clinical and Microbiological Evidence.Bioengineering (Basel, Switzerland) · 2026Review
- Immediate versus conventional loading implants with fixed prosthesis - A clinical and radiological study.Bioinformation · 2026Article
- Early Marginal Bone Loss as a Determinant Factor of the Prognosis Rate of Dental Implants: A Prospective Longitudinal Observational Study.Journal of International Society of Preventive & Community DentistryArticle
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionEarly marginal bone loss (EMBL) is a non-infective phenomenon occurring around the implant neck from placement to the first year of prosthetic function, being influenced by both surgical and prosthetic factors. This multi-center prospective study assesses the impact of different variables potentially influencing marginal bone stability during the period from crown delivery to 18 months of functional loading.
methodsForty-seven patients requiring a single posterior mandibular implant were selected according to specific criteria. Tissue-level implants were placed at different crestal bone levels based on vertical mucosal thickness and followed in an unsubmerged healing protocol, as described in a previous study evaluating peri-implant bone levels (PBL) from implant placement (T0) to crown delivery (T1). The present study continues this evaluation, focusing on MBL from T1 to 18 months post-loading (T2). Host-related factors (age, gender, smoking, history of periodontitis, vertical mucosal thickness) and specific prosthetic parameters, including crown mesio-distal dimension, emergence angle, and transmucosal collar height were recorded. Multiple linear regression analysis explored associations between MBL and prosthetic or patient-related factors, with significance set at p < 0.05.
resultsMarginal bone levels remained stable from T1 to T2, with no significant association between MBL and host-related factors or defined prosthetic variables. However, total MBL from T0 to T2 was significantly higher around implants with thin mucosa at T0 compared to medium and thick mucosa. Multivariate analysis (T0-T2) identified thin mucosa and smoking as significant MBL predictors.
conclusionFrom T1 to T2, marginal bone levels around tissue-level implants remain stable, with no significant influence from variables analyzed. Conversely, peri-implant bone resorption between T0 and T2 is significantly associated with thin mucosa (primarily affecting T0-T1) and smoking.
trial registrationwww. CLINICALTRIALS: gov: NCT05363306.
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