Evidence map›Paper›PMID 40500743›Full record

ReviewVirology journal2025

Strategies and scheming: the war between PRRSV and host cells.

Fan Gao, Guilan Wen

Abstract readReview
In one paragraph

Review in Virology journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Review
  7. Review
  8. KAP1 in antiviral immunity: dual roles in viral silencing and immune regulation.Frontiers in cellular and infection microbiology · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Fan GaoCollege of Animal Science, Guizhou University, Guiyang, 550000, China.
Guilan WenCollege of Animal Science, Guizhou University, Guiyang, 550000, China. glwen@gzu.edu.cn.

Funding

Guizhou Province Embryo Development and Embryo Implantation regulatory Mechanism research innovation team Talents of Guizhou, Science, and Technology Cooperation Platform-BQW[2024]007The National Natural Science Foundation, mechanism of action of apolipoprotein B mRNA editing enzyme catalytic-like protein 3F in PRRSV replication 32060794
6 · The paper itself

Abstract

Porcine reproductive and respiratory syndrome virus (PRRSV) is a far-reaching economic class of pathogen of swine breeding, causing substantial financial losses to the swine industry. Due to the lack of effective control measures and effective vaccines, the virus continues to persist and spread. PRRSV uses complex and tightly regulated processes to enter the host cells. In brief, the process can be divided into three phases: endocytosis, intracellular replication, and release. The virus employs host cell proteins and related pathways to achieve intracellular replication, evading the host's immune response. In response to exogenous intracellular pathogen infection, host cells utilize various strategies to antagonize the viral replication process. This review examines the multiple mechanisms by which PRRSV infects host cells and elucidates the pivotal roles of viral effectors during intracellular replication. In addition, it delves into the host cell response to PRRSV infection. These findings are essential for in-depth understanding and research on PRRSV infection strategies and identifying antiviral targets.

Indexed as

Host-Pathogen InteractionsPorcine Reproductive and Respiratory SyndromePorcine respiratory and reproductive syndrome virusVirus ReplicationAnimalsEndocytosisSwineEndocytosisImmune escapeInfection strategiesIntracellular replicationPRRSV

Identifiers

PMID40500743
PMCPMC12153163

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.