ReviewWorld journal of surgical oncology2025
Colonic endometriosis: from subtotal bowel obstruction to malignant transformation - a case series and literature review.
Review in World journal of surgical oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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7 authors.
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Abstract
backgroundColonic involvement due to endometriosis is a rare condition with a nonspecific clinical presentation. In rare instances, it may undergo malignant transformation, mimicking primary colorectal carcinoma and complicating clinical decision-making. CASE PRESENTATION: We present two cases illustrating the diverse clinical manifestations of colonic endometriosis. In Case 1, a female patient underwent appendectomy for abdominal pain, but further evaluation revealed full-thickness endometriosis of the sigmoid colon, causing subtotal occlusion. In Case 2, sigmoid endometriosis was discovered during endoscopic evaluation prompted by positive occult fecal blood testing. Histopathological analysis revealed malignant transformation to endometrioid adenocarcinoma. In both cases, definitive treatment was achieved via laparoscopic sigmoid resection, highlighting the role of laparoscopic surgery in managing such conditions.
conclusionsThe potential for malignant transformation of colonic endometriosis and its tendency to mimic colorectal carcinoma underscore the importance of proper tissue sampling methods and histopathological confirmation. A high index of suspicion and appropriate surgical intervention are key to effective management.
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