Evidence map›Paper›PMID 40500514›Full record

Trial reportEuropean archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery2025

Effectiveness of lifestyle-modification approach (a randomized-controlled program of diet restriction and treadmill walking exercise) on elderly's metabolic syndrome-associated subjective tinnitus.

Ali Mohamed Ali Ismail, Ahmed Mahmoud Nasr Tolba

Registry-linked trialAbstract readRandomized Controlled Trial
In one paragraph

Trial report in European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06702085 (Effects of Lifestyle Changes on Tinnitus in Older Adults With Metabolic Syndrome), which is not on this map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06702085 narecruitingnot on this map

Effects of Lifestyle Changes on Tinnitus in Older Adults With Metabolic Syndrome

TypeinterventionalSponsorCairo UniversityRan2024 to 2025Enrolled60ConditionsTinnitus, Metabolic Syndrome X, Obesity, ElderlyArmsLifestyle Management
3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Trial
  2. Trial
  3. Tinnitus in urban settings: insights into lifestyle and medical factors from the Hamburg City Health Study.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026
    Article
  4. Article
  5. Review
  6. Methodological considerations for lifestyle interventions in metabolic syndrome-associated tinnitus: the need for attention-matched controls and personalized exercise prescriptions.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026
    Article
  7. Article
  8. Response to the letter to editor regarding "Effectiveness of lifestyle-modification approach on elderly metabolic syndrome-associated subjective tinnitus''.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026
    Article
  9. Comment on "Effectiveness of lifestyle-modification approach (A randomized-controlled program of diet restriction and treadmill walking exercise) on elderly's metabolic syndrome-associated subjective tinnitus".European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026
    Article
  10. Article
  11. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Ali Mohamed Ali IsmailDepartment of Physical Therapy for Cardiovascular/Respiratory Disorder and Geriatrics, Faculty of Physical Therapy, Cairo University, Giza, Egypt. ali.mohamed@pt.cu.edu.eg.ORCID http://orcid.org/0000-0003-1447-8817
Ahmed Mahmoud Nasr TolbaBasic Science Department, Faculty of Physical Therapy, Delta University for Science and Technology, International Coastal Road, Gamassa, Dakahlia, Egypt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionChronic subjective tinnitus complaint (CSTC) is highly prevalent in metabolic syndrome (MS) elderly. In 60 obese MS elderly with CSTC, studying the response of CSTC-related discomfort, MS components, and CSTC severity to lifestyle-modification approach was the aim of this study.

methodsIn this randomized/controlled lifestyle-modification trial, the recruitment of 60 obese MS elderly with CSTC from a local general hospital was randomly executed. The recruited elderly with MS and CSTC were randomly assigned to a study group (performed lifestyle-modification approach and the components of this 12-week approach were on-electrical treadmill walking plus diet restriction) or waitlist/control group (n = 30). Besides MS components/variables such as elderly's waist circumference (WC), elderly's fasting glucose in serum (FGIS), elderly's triglycerides (TriGly), elderly's blood pressure, and elderly's high-density lipoprotein (HDLipo), lifestyle-modification approach's outcomes of this trial were elderly's body mass index, visual analogue scale (VAS) of CSTC-related discomfort, tinnitus handicap inventory (THI), and VAS of CSTC severity.

resultsTracking all outcomes of this lifestyle-modification approach in the study group (n = 30 MS elderly with CSTC) showed significant improvements while the control group's outcome did not improve.

conclusionBMI, VAS of CSTC severity, components of MS (WC, FGIS, blood pressure, TriGly, and HDLipo), THI, and VAS of CSTC-related discomfort could be improved after involving obese MS elderly with CSTS in a 12-week lifestyle-modification approach. TRIAL REGISTRATION NUMBER: NCT06702085.

Indexed as

Diet, ReducingExercise TherapyMetabolic SyndromeObesityTinnitusWalkingAgedFemaleHumansLife StyleMaleMiddle AgedTreatment OutcomeDietElderlyExerciseMetabolic syndromeTinnitus

Identifiers

PMID40500514
PMCPMC12399441

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.