Evidence map›Paper›PMID 40500496›Full record

ReviewAdvances in neurobiology2025

Morphology of Oligodendroglial Cells.

Arthur Butt, Adam Willis, Rachel Stevens, Ian Hunter, Akiko Nishiyama

Abstract readReview
PubMed Publisher
In one paragraph

Review in Advances in neurobiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Arthur ButtSchool of Medicine, Pharmacy and Biomedical Science, University of Portsmouth, Portsmouth, UK. Arthur.butt@port.ac.uk.
Adam WillisSchool of Medicine, Pharmacy and Biomedical Science, University of Portsmouth, Portsmouth, UK.
Rachel StevensSchool of Medicine, Pharmacy and Biomedical Science, University of Portsmouth, Portsmouth, UK.
Ian HunterSchool of Medicine, Pharmacy and Biomedical Science, University of Portsmouth, Portsmouth, UK.
Akiko NishiyamaDepartment of Physiology and Neurobiology, University of Connecticut, Storrs, CT, USA. akiko.nishiyama@uconn.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Oligodendrocytes are cells in the central nervous system that are specialised to form myelin sheaths around axons. They are generated from oligodendrocyte precursor cells that persist in the adult brain and are responsible for myelin plasticity that is essential for learning and repair in pathology. Oligodendrocytes exhibit morphological and molecular heterogeneity, and, besides their role in myelination, they provide metabolic and homeostatic support for neurones. In addition, some oligodendrocytes exhibit an immune function as antigen-presenting cells under certain conditions. The myelinating function of oligodendrocytes is essential for nervous system operational integrity, and the loss of myelin leads to neurodegeneration and an irreversible loss of function.

Indexed as

Myelin SheathOligodendrogliaAnimalsHumansAxonMyelinNeuroneOligodendrocyteOligodendrocyte precursor cellOligodendrogliaPerineuronal oligodendrocyteSatellite oligodendrocyte

Identifiers

PMID40500496

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.