Evidence map›Paper›PMID 40500494›Full record

ReviewAdvances in neurobiology2025

Development of Oligodendroglia and Myelin.

Hao Huang, Xiaofeng Xu, Mengsheng Qiu

Abstract readReview
PubMed Publisher
In one paragraph

Review in Advances in neurobiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Hao HuangZhejiang Key Laboratory of Organ Development and Regeneration, College of Life and Environmental Sciences, Hangzhou Normal University, Hangzhou, China.
Xiaofeng XuZhejiang Key Laboratory of Organ Development and Regeneration, College of Life and Environmental Sciences, Hangzhou Normal University, Hangzhou, China.
Mengsheng QiuZhejiang Key Laboratory of Organ Development and Regeneration, College of Life and Environmental Sciences, Hangzhou Normal University, Hangzhou, China. msqiu@hznu.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Myelin sheaths formed by oligodendrocytes (OLs) wrap around neuronal axons and allow for saltatory conduction of nerve impulses, significantly increasing the speed of electrical signal transmission. The development of oligodendrocyte lineage consists of several coordinated steps. Briefly, oligodendrocyte precursor cells (OPCs) are first generated from neural precursor cells of certain neuroepithelial regions, and then they proliferate and migrate to other regions of the central nervous system (CNS), where they differentiate into oligodendrocytes and form myelin sheaths around the axons of neurons. These developmental processes are tightly and precisely regulated during animal development by a cohort of intracellular molecular and extracellular signals.

Indexed as

Central Nervous SystemMyelin SheathOligodendrogliaAnimalsAxonsCell DifferentiationHumansDifferentiationMyelinationOligodendrocytesOPCsProliferationSpecification

Identifiers

PMID40500494

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.