Evidence map›Paper›PMID 40500437›Full record

ArticleNature2025

Developmental trajectory and evolutionary origin of thymic mimetic cells.

Anja Nusser, Oliver S Thomas, Gaoqun Zhang, Daisuke Nagakubo, Laura Arrigoni, Brigitte Krauth, Thomas Boehm

Abstract read
In one paragraph

Article in Nature, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Runx3 instructs AireJournal of autoimmunity · 2026
    Article
  6. Review
  7. Review
  8. Review
  9. LampreyProceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  10. Article
  11. Thymic central tolerance takes centre stage in autoimmune disease.The Lancet regional health. Western Pacific · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Anja Nusser *Department of Developmental Immunology, Max Planck Institute of Immunobiology and Epigenetics, Freiburg, Germany.ORCID 0000-0002-8157-0560
Oliver S Thomas *Department of Developmental Immunology, Max Planck Institute of Immunobiology and Epigenetics, Freiburg, Germany.ORCID 0000-0003-1949-0938
Gaoqun Zhang *Department of Developmental Immunology, Max Planck Institute of Immunobiology and Epigenetics, Freiburg, Germany.
Daisuke NagakuboDepartment of Developmental Immunology, Max Planck Institute of Immunobiology and Epigenetics, Freiburg, Germany.ORCID 0000-0003-1213-1246
Laura ArrigoniDeep Sequencing Facility, Max Planck Institute of Immunobiology and Epigenetics, Freiburg, Germany.
Brigitte KrauthDepartment of Developmental Immunology, Max Planck Institute of Immunobiology and Epigenetics, Freiburg, Germany.
Thomas BoehmDepartment of Developmental Immunology, Max Planck Institute of Immunobiology and Epigenetics, Freiburg, Germany. boehm@ie-freiburg.mpg.de.ORCID 0000-0001-5172-7478

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The generation of self-tolerant repertoires of T cells depends on the expression of peripheral self antigens in the thymic epithelium

Indexed as

Biological EvolutionThymus GlandAnimalsBasic Helix-Loop-Helix ProteinsCell DifferentiationCellular MicroenvironmentEpithelial CellsFemaleForkhead Transcription FactorsMaleMiceBasic Helix-Loop-Helix ProteinsForkhead Transcription FactorsWhn protein

Identifiers

PMID40500437
PMCPMC12286861

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.