Evidence map›Paper›PMID 40500428›Full record

ArticleLangenbeck's archives of surgery2025

Efficacy of preoperative endoscopic nasobiliary drainage tube placement for liver cancer adjacent to the hepatic hilum.

Sho Kiritani, Yoshihiro Ono, Takashi Sasaki, Atsushi Oba, Takafumi Sato, Hiromichi Ito, Yosuke Inoue, Masato Ozaka, Naoki Sasahira, Akio Saiura and 1 more

Abstract read
In one paragraph

Article in Langenbeck's archives of surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Sho KiritaniDivision of Hepatobiliary and Pancreatic Surgery, Cancer Institute Hospital, Japanese Foundation for Cancer Research, 3-8-31 Ariake, Koto-Ku, Tokyo, 135-8550, Japan.
Yoshihiro OnoDivision of Hepatobiliary and Pancreatic Surgery, Cancer Institute Hospital, Japanese Foundation for Cancer Research, 3-8-31 Ariake, Koto-Ku, Tokyo, 135-8550, Japan. yoshihiro.ono@jfcr.or.jp.
Takashi SasakiDepartment of Hepato-Biliary-Pancreatic Medicine, Cancer Institute Hospital, Japanese Foundation for Cancer Research, Tokyo, 135-8550, Japan.
Atsushi ObaDivision of Hepatobiliary and Pancreatic Surgery, Cancer Institute Hospital, Japanese Foundation for Cancer Research, 3-8-31 Ariake, Koto-Ku, Tokyo, 135-8550, Japan.
Takafumi SatoDivision of Hepatobiliary and Pancreatic Surgery, Cancer Institute Hospital, Japanese Foundation for Cancer Research, 3-8-31 Ariake, Koto-Ku, Tokyo, 135-8550, Japan.
Hiromichi ItoDivision of Hepatobiliary and Pancreatic Surgery, Cancer Institute Hospital, Japanese Foundation for Cancer Research, 3-8-31 Ariake, Koto-Ku, Tokyo, 135-8550, Japan.
Yosuke InoueDivision of Hepatobiliary and Pancreatic Surgery, Cancer Institute Hospital, Japanese Foundation for Cancer Research, 3-8-31 Ariake, Koto-Ku, Tokyo, 135-8550, Japan.
Masato OzakaDepartment of Hepato-Biliary-Pancreatic Medicine, Cancer Institute Hospital, Japanese Foundation for Cancer Research, Tokyo, 135-8550, Japan.
Naoki SasahiraDepartment of Hepato-Biliary-Pancreatic Medicine, Cancer Institute Hospital, Japanese Foundation for Cancer Research, Tokyo, 135-8550, Japan.
Akio SaiuraDepartment of Hepatobiliary-Pancreatic Surgery, Juntendo University School of Medicine, Tokyo, 113-8431, Japan.
Yu TakahashiDivision of Hepatobiliary and Pancreatic Surgery, Cancer Institute Hospital, Japanese Foundation for Cancer Research, 3-8-31 Ariake, Koto-Ku, Tokyo, 135-8550, Japan. yu.takahashi@jfcr.or.jp.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeSurgical resection of liver cancer adjacent to the hepatic hilum is challenging, especially in balancing remnant liver volume preservation with bile duct safety. This study evaluated the efficacy of preoperative endoscopic nasobiliary drainage (ENBD) tube placement as an intraoperative guide for bile duct preservation during liver resection.

methodsSixteen patients with liver cancer adjacent to the hepatic hilum who underwent preoperative ENBD tube placement and curative liver resection from 2016 to 2023 were retrospectively reviewed. Liver resection was performed along the bile duct where the ENBD tube was placed, preserving that bile ducts and liver section. Risks associated with ENBD tube insertion, the short-term outcomes, and local recurrence incidence were assessed.

resultsThe ENBD tube was placed a median 3 days preoperatively in the right lobe in 12 patients and the left lobe in four. No patient experienced post-endoscopic retrograde cholangiopancreatography pancreatitis, and all patients underwent surgery as scheduled. Surgeons could preserve the bile ducts nearby the tumor by directly palpating the ENBD tube and/or using air cholangiography in all cases. Clinically relevant bile leakage occurred in one patient (6.3%). The median time to discharge was 12 days, with no significant posthepatectomy liver failure and mortality. All patients achieved negative surgical margins, and only one patient experienced local recurrence (6.3%).

conclusionPreoperative ENBD tube placement is a safe, collaborative endoscopic-surgical technique that facilitates optimal liver preservation and acceptable local control for liver cancer adjacent to the hepatic hilum.

Indexed as

DrainageHepatectomyLiver NeoplasmsPreoperative CareAdultAgedFemaleHumansMaleMiddle AgedRetrospective StudiesTreatment OutcomeEndoscopic nasobiliary drainage tubeHepatectomyHepatic hilumLiver cancerParenchyma sparing surgery

Identifiers

PMID40500428
PMCPMC12158846

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.