Evidence map›Paper›PMID 40500280›Full record

ReviewSchizophrenia (Heidelberg, Germany)2025

Neuromodulation in the treatment of social cognition dysfunction in Schizophrenia: a systematic review.

Marta Moura Neves, Fabiana Ventura, Nuno Madeira

Abstract readReview
In one paragraph

Review in Schizophrenia (Heidelberg, Germany), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Marta Moura Neves *Department of Psychiatry and Mental Health, Coimbra Local Health Unit, Coimbra, Portugal.ORCID http://orcid.org/0009-0009-2630-3484
Fabiana Ventura *Department of Psychiatry and Mental Health, Coimbra Local Health Unit, Coimbra, Portugal.ORCID http://orcid.org/0000-0001-9171-0291
Nuno MadeiraDepartment of Psychiatry and Mental Health, Coimbra Local Health Unit, Coimbra, Portugal. nmadeira@uc.pt.ORCID http://orcid.org/0000-0001-5009-8841

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDeficits in social cognition are significant barriers to functional living for individuals with schizophrenia. Although these symptoms have garnered increasing research attention, an effective treatment remains elusive. This systematic review evaluates the use of neuromodulation techniques in treating social cognition deficits in schizophrenia.

methodsWe conducted a literature search in MEDLINE/PubMed, Web of Science, The Cochrane Library, and Embase databases, adhering to PRISMA guidelines. We included randomized, sham-controlled trials, non-controlled and/or open-label trials that assessed the efficacy of neuromodulation in patients diagnosed with schizophrenia (as per the DSM-III or later editions, or ICD equivalents), aged over 18 years.

resultsThirteen papers (1 on ECT, 4 on rTMS, and 8 on tES), including 11 RCTs, met the inclusion criteria. Seven of the thirteen analyzed studies indicated improvements in certain domains of social cognition associated with neuromodulation treatments.

conclusionsNeuromodulation techniques improved some domains of social cognition in individuals with schizophrenia. Further research is required to develop robust treatment protocols with proven efficacy in improving social cognition.

Identifiers

PMID40500280
PMCPMC12159152

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.