ArticlePrenatal diagnosis2025
Diffusion Tensor Imaging of Fetuses With Congenital Diaphragmatic Hernia.
Article in Prenatal diagnosis, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
- In utero hematopoietic cell transplantation in fetuses with α-thalassemia major: a phase 1 clinical trial.Blood advances · 2026Article
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Authors and funding
7 authors.
Funding
Abstract
objectiveTo evaluate differences in diffusion tensor imaging (DTI) parameters in the brain between fetuses with congenital diaphragmatic hernia (CDH) and age-matched controls.
methodThis retrospective IRB-approved study included fetal MRIs for CDH and gestational age (GA) matched controls with lung pathology other than CDH with normal fetal brains. Fetal DTI data were acquired in 15 noncollinear diffusion-weighting directions with the b-value at 600 s/mm
resultsTwenty-eight controls (27.3 ± 4.1 weeks GA) and 26 CDH (28.1 ± 4.2 weeks GA) fetuses were included. Fractional anisotropy (FA) values were significantly higher (p < 0.05) in CDH fetuses relative to controls in 12 of 50 white matter (WM) regions examined based on ANCOVA controlling for GA. After controlling for GA, sex, and CDH side, FA values in the CDH fetuses had a significant positive correlation with observed-to-expected lung volumes in 20 of 50 WM regions and with percent predicted lung volumes in 29 of 50 WM regions.
conclusionOur data demonstrate evidence of microstructural differences based on DTI indices in the brain between CDH fetuses and age-matched controls along with correlation with the degree of pulmonary hypoplasia.
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