ArticleThe Journal of reproduction and development2025
A prospective randomized trial comparing dephereline and busereline for ovulation induction in heat-stressed lactating dairy cows.
Article in The Journal of reproduction and development, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Climate change is causing heat stress (HS) in dairy cattle. This study aimed to compare the clinical efficacy of two GnRH synthetic analogs, dephereline and busereline, as ovulation inducers under HS conditions. The study population comprised 1,000 lactating dairy cows showing signs of spontaneous estrus which were assigned to the groups: DEPH (489 cows receiving 100 µg of dephereline) and BUS (511 cows receiving 10 µg of busereline) at the time of insemination. Cows were included only once in the study. Treatment with busereline increased the risk of multiple ovulations and twin pregnancies, with an odds ratio (OR) of 1.6, and twin pregnancies, with an OR of 2.8, when compared with dephereline. The likelihood of pregnancy in multiple-ovulating cows was significantly higher in the DEPH group than the BUS group. Collectively, our results comparing two ovulation inducers showed that dephereline treatment may improve the fertility of lactating dairy cows under HS conditions.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.