Evidence map›Paper›PMID 40499922›Full record

GuidelineRheumatology (Oxford, England)2025

The 2025 British Society for Rheumatology management recommendations for ANCA-associated vasculitis.

Kathryn Biddle, Judith Jade, Harold Wilson-Morkeh, Madura Adikari, Chadwan Al Yaghchi, Zoi Anastasa, Neil Basu, Paul Brogan, Dimitrios Chanouzas, Shouvik Dass and 22 more

Erratum issuedAbstract readPractice GuidelineSystematic Review
In one paragraph

Guideline in Rheumatology (Oxford, England), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Observational
  8. Review
  9. Eosinophilic gastrointestinal diseases.Nature reviews. Disease primers · 2026
    Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Observational
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

32 authors.

Kathryn BiddleDepartment of Rheumatology, Guy's and St Thomas' NHS Foundation Trust, London, UK.ORCID 0000-0001-5267-200X
Judith JadeDepartment of Rheumatology, Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, UK.
Harold Wilson-MorkehDepartment of Rheumatology, Imperial College Healthcare NHS Trust, London, UK.
Madura AdikariDepartment of Rheumatology, Royal Chesterfield NHS Foundation Trust, Chesterfield, UK.
Chadwan Al YaghchiENT Department, Imperial College Healthcare NHS Trust, London, UK.
Zoi AnastasaExpert by Experience, Plymouth, UK.
Neil BasuDepartment of Rheumatology, University of Glasgow, Glasgow, UK.
Paul BroganDepartment of Rheumatology, Great Ormond Street Hospital NHS Foundation Trust, London, UK.
Dimitrios ChanouzasDepartment of Nephrology, University Hospitals Birmingham NHS Foundation Trust, Birmingham, Birmingham Health Partners UK, Birmingham, UK.
Shouvik DassDepartment of Rheumatology, Leeds Teaching Hospitals NHS Trust, Leeds, UK.
David D'CruzDepartment of Rheumatology, Guy's and St Thomas' NHS Foundation Trust, London, UK.
Marcos Martinez Del PeroENT Department, Cambridge University Hospital, Cambridge, UK.
Emmandeep DhillonDepartment of Rheumatology, New Cross Hospital, Royal Wolverhampton NHS Trust, Wolverhampton, UK.
Georgina DuckerDepartment of Rheumatology, Norfolk and Norwich University Hospital, Norwich, UK.
Siân GriffinDepartment of Nephrology and Transplantation, University Hospital of Wales, Cardiff, UK.
Rosemary J HollickAberdeen Centre for Arthritis and Musculoskeletal Health (Epidemiology Group), University of Aberdeen, Aberdeen, UK.ORCID 0000-0001-6558-7189
David JacksonDepartment of Respiratory Medicine, Guy's and St Thomas' NHS Trust, London, UK.
Catherine KingDepartment of Nephrology, University Hospitals Birmingham NHS Foundation Trust, Birmingham, Birmingham Health Partners UK, Birmingham, UK.
Matko MarlaisDepartment of Nephrology, Great Ormond Street Hospital for Children NHS Foundation Trust, London, UK.
Alice MasonDepartment of Rheumatology, University Hospital Southampton, Southampton, UK.
Stephen McAdooImmunology and Immunotherapy Department, Imperial College London, London, UK.
Devesh MewarDepartment of Rheumatology, Liverpool University Hospitals NHS Foundation Trust, Liverpool, UK.
Janice MooneySchool of Health, Education, Policing and Sciences, Staffordshire University, Stafford, UK.
Eleana NtatsakiDepartment of Rheumatology, East Suffolk and North Essex NHS Foundation Trust, Ipswich, UK.
Fiona PearceClinical Sciences Building, City Hospital Campus, University of Nottingham, Nottingham, UK.ORCID 0000-0003-2884-1998
Benjamin RhodesDepartment of Rheumatology, University Hospitals Birmingham NHS Trust, Birmingham, UK.ORCID 0000-0001-7554-5409
Hitasha RupaniDepartment of Respiratory Medicine, University Hospital Southampton, Southampton, UK.
Alan SalamaUniversity College London Centre for Kidney and Bladder Health, Royal Free Hospital, London, UK.ORCID 0000-0002-9255-9092
Salman SiddiquiNational Heart and Lung Institute, Imperial College London, London, UK.
Rona SmithRenal Department, University of Cambridge, Cambridge, UK.
Lorraine HarperDepartment of Nephrology, University Hospitals Birmingham NHS Foundation Trust, Birmingham, Birmingham Health Partners UK, Birmingham, UK.ORCID 0000-0003-1343-9234
British Society for Rheumatology Guideline Steering Group

Funding

AstraZenecaBritish Society for Rheumatology
6 · The paper itself

Abstract

ANCA-associated vasculitis (AAV) is comprised of three specific conditions: granulomatosis with polyangiitis (GPA), microscopic polyangiitis (MPA) and eosinophilic granulomatosis with polyangiitis (EGPA). Since the publication of the last British Society for Rheumatology (BSR) and British Health Professionals in Rheumatology (BHPR) guideline for the management of adults with AAV in 2014, a plethora of randomized controlled trials, additional research and recommendations have provided novel insights into how the management of AAV can be optimized, thus improving patient quality of life. The BSR AAV Working Group (WG) reviewed published guidelines, undertook a systematic literature review and utilized expertise from specialist vasculitis centres across the UK and patient representatives to formulate a list of 26 recommendations with corresponding strength of agreement (SOA) scores. Recommendations were updated from the published 2014 BSR and BHPR guideline. The 26 recommendations encompassed five key domains: 1. Treatment for GPA and MPA; 2. Management of subglottic stenosis and ear, nose and throat (ENT) manifestations of AAV; 3. Management and treatment for EGPA; 4. Service specifications; 5. Patient education and support. These recommendations provide an update on care delivery of AAV based on current evidence and specialist opinion. In addition, we have provided research and audit recommendations to support equitable access to care and improve health outcomes. The lay summary that accompanies this abstract can be found in Supplementary Data S1, available at Rheumatology online.

Indexed as

Anti-Neutrophil Cytoplasmic Antibody-Associated VasculitisDisease ManagementHumansRheumatologySocieties, MedicalUnited KingdomANCA vasculitistreatment

Identifiers

PMID40499922
PMCPMC12316377

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.