Evidence map›Paper›PMID 40499880›Full record

ArticleRespiratory physiology & neurobiology

Spirometric and exercise ventilatory predictors of expiratory flow-limitation in adults with normal and mildly-obstructed airways.

Hans Christian Haverkamp, Peter Luu, Yannick Molgat-Seon, Gregory Petrics, Sterling McPherson

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Article in Respiratory physiology & neurobiology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

5 authors.

Hans Christian HaverkampWashington State University-Health Sciences Spokane College of Medicine, Department of Nutrition and Exercise Physiology, Spokane, WA, USA. Electronic address: Hans.Haverkamp@wsu.edu.
Peter LuuWashington State University-Health Sciences Spokane College of Medicine, Department of Nutrition and Exercise Physiology, Spokane, WA, USA.
Yannick Molgat-SeonUniversity of Winnipeg, Department of Kinesiology and Applied Health, Winnipeg, Manitoba, Canada.
Gregory PetricsVermont State University-Johnson, Department of Mathematics, Johnson, VT, USA.
Sterling McPhersonWashington State University-Health Sciences Spokane College of Medicine, Department of Community and Behavioral Health, Spokane, WA, USA.

Funding

Vermont INBRE Administrative Supplement 2024 AWD 118P20GM103449 · NIGMS · UNIVERSITY OF VERMONT & ST AGRIC COLLEGE · PI CHRISTOPHER S FRANCKLYN · 2012 to 2026
$58.4M
NIGMS NIH HHS P20 GM103449
6 · The paper itself

Abstract

purposeWe determined the resting spirometric and exercise ventilatory variables that are predictive of exercise expiratory flow limitation (EFL) in a group of adults in whom airway function varied from mildly obstructed to above predicted values.

methodsWe studied n = 25 adults (16/9 M/F; age, 31 years) in whom forced expiratory volume in 1 s (FEV

resultsA set of spirometric variables explained 75 % and 73 % of the variance in %-EFL and the presence of EFL using MR

conclusionsGiven the difficulty of measuring EFL during exercise, our findings suggest that integrating additional measurements reflecting ventilatory capacity (i.e., spirometry) and demand (exercise measurements), including dynamic operating lung volumes, in clinical exercise testing will improve assessment of exercise ventilatory constraint.

Indexed as

Airway ObstructionExercisePulmonary VentilationSpirometryAdultExercise TestFemaleForced Expiratory VolumeHumansMaleTidal VolumeYoung AdultExercise ventilationExpiratory flow-limitationPulmonary functionSpirometryVentilatory mechanical constraints

Identifiers

PMID40499880
PMCPMC13093914

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.