ArticleInternational journal of surgery case reports2025
Double trouble: Tumor-to-tumor metastasis of breast cancer into a thyroid papillary carcinoma - Case report and review of literature.
Article in International journal of surgery case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- Development of a risk prediction model for second primary thyroid cancer in female breast cancer patients based on machine learning algorithms.Scientific reports · 2026Article
- Metastasis of lung adenocarcinoma to follicular thyroid carcinoma combined with papillary thyroid carcinoma in the contralateral lobe: A case report.Oncology letters · 2026Article
- Case Report: A rare case of thyroid metastasis from breast cancer.Frontiers in oncology · 2025Article
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6 authors.
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Abstract
introduction and importanceTumor-to-tumor metastasis is a rare and challenging phenomenon, particularly involving the thyroid gland. Breast cancer metastasizing into the thyroid gland with a coexisting papillary thyroid carcinoma is an extremely rare situation, with few cases reported in the literature. Our aim was to report a rare incidence of this association, along with a literature review of similar cases. CASE PRESENTATION: We present the case of a 63-year-old woman with a history of invasive lobular breast carcinoma who developed a right thyroid nodule. The patient underwent total thyroidectomy and pathology revealed metastatic breast carcinoma with a coexistent papillary thyroid carcinoma in the same lobe. CLINICAL DISCUSSION: Metastatic breast cancer to the thyroid accounts for only 1 %-3 % of all thyroid malignancies, despite the thyroid's rich vascularity. These metastases can mimic a primary thyroid tumor. Only definitive histology can confirm the metastatic origin in these cases.
conclusionThis case highlights the diagnostic and therapeutic challenges encountered when facing tumor-to-tumor metastasis. Despite its rarity, awareness of this entity is crucial and requires close thyroid monitoring in breast cancer survivors.
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