Evidence map›Paper›PMID 40499439›Full record

ArticleInternational journal of surgery case reports2025

Hyperthyroidism with a normal cervical thyroid gland: A rare case report of thyroid hormone releasing mass in the chest.

Arooj Fatima, Shahmir Ghafoor, Areeba Inam, Aneeq Shahzad, Waseem Sajjad

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Article in International journal of surgery case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Arooj FatimaCMH Kharian Medical College, Gujrat, Pakistan.
Shahmir GhafoorPunjab Medical College, Faisalabad, Pakistan.
Areeba InamAyub Medical College, Abbotabad, Pakistan.
Aneeq ShahzadQuetta Institute of Medical Sciences, Quetta, Pakistan.
Waseem SajjadKing Edward Medical University, Mayo Hospital, Lahore, Pakistan. Electronic address: waseemsajjad2093@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introduction and importanceEctopic thyroid tissue is an uncommon developmental anomaly, particularly when located in the chest, making its diagnosis and management complex. When hyperthyroidism presents in a patient with a normal cervical thyroid gland, it may obscure the presence of ectopic functioning thyroid tissue, especially in unusual locations like the thoracic cavity. CASE PRESENTATION: We present the case of a 35-year-old female with biochemical evidence of hyperthyroidism but a clinically and radiologically normal thyroid gland in the neck. Further imaging uncovered a chest mass, initially suspected to be malignant. Surgical excision and histopathological analysis confirmed it as ectopic thyroid tissue. Postoperative follow-up showed normalization of thyroid hormone levels, and the patient had an uneventful recovery. CLINICAL DISCUSSION: This case illustrates a rare presentation of hyperthyroidism caused by ectopic thyroid tissue in the absence of cervical thyroid abnormalities. A thorough diagnostic workup is essential to rule out malignancy and confirm ectopic thyroid origin. Surgical resection remains the definitive treatment, often resulting in hormonal normalization.

conclusionEctopic thyroid tissue should be considered in cases of unexplained hyperthyroidism, especially when the cervical thyroid appears normal. Awareness of this rare condition can prevent misdiagnosis and help guide appropriate therapeutic strategies.

Indexed as

HyperthyroidismMediastinal neoplasmThoracotomyThyroid dysgenesis

Identifiers

PMID40499439
PMCPMC12179723

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