ArticleAge and ageing2025
Should octogenarians and people aged 90 years and over be treated separately in studies of stroke? An evaluation of national audit data.
Article in Age and ageing, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionPopulation studies frequently use ≥80 years for defining 'very old' but as mean life expectancy frequently exceeds 80 years internationally, this may no longer be appropriate. Those ≥90 years now represent a significant proportion of stroke patients. We examined national data to examine the differences between those 80-89 years and those 90+ years.Methods Data from the Irish National Audit of Stroke (2017-22 inclusive), including demographic, admission and outcome data, including prestroke and discharge modified Rankin Scores (mRS), were analysed. Proportional data were analysed using Chi-square statistics.
resultsData on 26 829 individual stroke events were analysed of which 7329 (27.3%) were in people 80-89 years; 52.8% were women. 1708 events occurred in people ≥90 (6.4%); 70.0% were women. 73.7% of those 80-89 years had mRS < 3 prestroke vs 51.3% of those ≥90 (P < .001). In hospital mortality for people ≥90 was higher (26.8% vs 17.4% P < .001) and they were less likely to have mRS < 3 at discharge (17.0% vs 35.8% P < .001). Proportion of haemorrhagic stroke was significantly lower in those ≥90 (15.3% vs 12.9% P = .015). Only one haemorrhage was reported amongst 31 people ≥100 years. The proportion of atrial fibrillation (AF) detected following stroke was not significantly different (≥90 years: 33.9%, 80-89 years, 32.4% P = .38).On logistic regression, nonrecovery to independence (mRS >2) in those ≥90 was associated with prestroke mRS, haemorrhagic stroke, AF and being thrombolysed.
conclusionThere are differences in profiles and outcomes between the groups, and it is now more appropriate to consider them separately.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.