Evidence map›Paper›PMID 40499079›Full record

Trial reportClinical and experimental dental research2025

A Randomized Crossover Trial Assessing Plaque Regrowth Dynamics in Adults With Use of an Oscillating-Rotating Electric Toothbrush Versus a Manual Toothbrush Measured by Digital Plaque Image Analysis.

Priscila Ferrari Peron, Ralf Adam, Julie Grender, Uta Mesples, Phyllis Hoke, Mike Rubush, Mary Kay Anastasia, Christina Erbe

Abstract readRandomized Controlled TrialComparative Study
In one paragraph

Trial report in Clinical and experimental dental research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Priscila Ferrari PeronDepartment of Dentofacial Orthopedics & Orthodontics, University Medical Center of the Johannes Gutenberg-University, Mainz, Germany.
Ralf AdamProcter & Gamble Service GmbH, German Innovation Center, Kronberg, Germany.
Julie GrenderThe Procter & Gamble Company, Mason Business Center, Mason, Ohio, USA.
Uta MesplesProcter & Gamble Service GmbH, German Innovation Center, Kronberg, Germany.
Phyllis HokeThe Procter & Gamble Company, Mason Business Center, Mason, Ohio, USA.
Mike RubushThe Procter & Gamble Company, Mason Business Center, Mason, Ohio, USA.
Mary Kay AnastasiaThe Procter & Gamble Company, Mason Business Center, Mason, Ohio, USA.
Christina ErbeDepartment of Dentofacial Orthopedics & Orthodontics, University Medical Center of the Johannes Gutenberg-University, Mainz, Germany.ORCID 0000-0003-1950-640X

Funding

This study was supported by the Procter & Gamble Company.
6 · The paper itself

Abstract

objectivesThis randomized crossover trial involving adult participants with ≥ 10% plaque coverage on anterior teeth compared dental plaque regrowth dynamics between an oscillating-rotating (O-R) electric toothbrush and a manual toothbrush using Digital Plaque Imaging Analysis. MATERIAL AND

methodsThirty-four participants were randomized to one of 4 treatment sequences, each having four 8-day treatment periods. Participants brushed twice daily with the assigned toothbrush. Morning and afternoon plaque were evaluated on Days 1, 3, and 8. The primary variable was afternoon percent plaque coverage, using repeated measures analysis from Days 1, 3, and 8.

resultsThe O-R toothbrush produced lower mean plaque levels versus the manual toothbrush for all endpoints (p ≤ 0.001). The benefit for the O-R toothbrush increased over time, demonstrating 16.4% (p = 0.001) and 28.1% (p < 0.001) lower afternoon plaque levels on Days 1 and 8, respectively, compared to the manual brush. Trends were similar for morning plaque. Repeated measures analyses showed a 21.2% reduction in overall afternoon plaque and a 23.5% reduction in overall morning plaque for the O-R brush versus the manual brush (p < 0.001).

conclusionsThe O-R toothbrush controlled plaque regrowth better than a manual toothbrush and should be considered to reduce plaque-related diseases as part of a generalized prophylaxis and treatment plan.

trial registrationISRCTN Registry: ISRCTN 28649560.

Indexed as

Dental PlaqueToothbrushingAdultCross-Over StudiesEquipment DesignFemaleHumansImage Processing, Computer-AssistedMaleMiddle AgedYoung Adultdental plaquedigital imagingelectric toothbrushoscillating‐rotating

Identifiers

PMID40499079
PMCPMC12156918

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.