Evidence map›Paper›PMID 40499056›Full record

ArticleJCO global oncology2025

Cervical Cancer Outcomes in Mozambique: Impact of an International Gynecologic Oncology Training Program.

Ricardina Rangeiro, Andre Lopes, Mark F Munsell, Dercia Changule, Siro Daud, Calisto Ferreira, Magda Ribeiro, Flora Mabota, Elvira Luis, Agostinho Daniel and 11 more

Abstract read
In one paragraph

Article in JCO global oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors.

Ricardina RangeiroHospital Central de Maputo, Maputo, Mozambique.ORCID 0000-0003-3782-8234
Andre LopesA. C. Camargo Cancer Center, São Paulo, Brazil.ORCID 0000-0002-4986-8738
Mark F MunsellThe University of Texas MD Anderson Cancer Center, Houston, TX.ORCID 0000-0001-9654-4958
Dercia ChanguleHospital Central de Maputo, Maputo, Mozambique.ORCID 0009-0003-0162-8879
Siro DaudHospital Central de Maputo, Maputo, Mozambique.
Calisto FerreiraUniversidade Unilúrio, Nampula, Mozambique.
Magda RibeiroHospital Central de Maputo, Maputo, Mozambique.
Flora MabotaUniversidade Eduardo Mondlane (UEM), Maputo, Mozambique.
Elvira LuisHospital Central de Maputo, Maputo, Mozambique.
Agostinho DanielHospital Central de Maputo, Maputo, Mozambique.
Edgar TsambeHospital Central de Maputo, Maputo, Mozambique.
Celso BilaHospital Central de Maputo, Maputo, Mozambique.
Georgia Fontes-CintraInstituto Brasileiro de Controle do Cancer, São Paulo, Brazil.ORCID 0000-0002-6463-7268
Renato Moretti-MarquesHospital Israelita Albert Einstein, São Paulo, Brazil.ORCID 0000-0001-9997-6668
Marcelo VieiraBeneficência Portuguesa, São Paulo, Brazil.
Vanessa Alvarenga-BezerraHospital Israelita Albert Einstein, São Paulo, Brazil.ORCID 0000-0003-2436-5939
Carla CarrilhoHospital Central de Maputo, Maputo, Mozambique.ORCID 0000-0003-0208-7309
Ellen BakerThe University of Texas MD Anderson Cancer Center, Houston, TX.
Cesaltina LorenzoniHospital Central de Maputo, Maputo, Mozambique.
Kathleen M SchmelerThe University of Texas MD Anderson Cancer Center, Houston, TX.ORCID 0000-0002-9670-4189
Mila P SalcedoThe University of Texas MD Anderson Cancer Center, Houston, TX.ORCID 0000-0002-6375-0736

Funding

Tumor Evolution and Metastasis ProgramP30CA016672 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI Fabien Delerue · 1985 to 2026
$290.8M
NCI NIH HHS P30 CA016672
6 · The paper itself

Abstract

purposeCervical cancer is the most common cancer among women in Mozambique and is a major health burden. Surgery for cervical cancer is currently performed at only one hospital in the country, Maputo Central Hospital. Before 2020, there were no gynecologists in Mozambique trained to care for women with cervical cancer. In 2017, the International Gynecologic Cancer Society (IGCS) started a gynecologic oncology training program in Mozambique, and in 2020, the first three fellows graduated from this program. The main objective of this study was to report the outcomes of patients with cervical cancer who were treated surgically by the three newly trained Mozambican gynecologic oncologists.

methodsWe performed a retrospective chart review of women diagnosed with cervical cancer who underwent surgical treatment by the Mozambican gynecologic oncologists between November 2020 and October 2022. The outcome of interest was survival at 2 years.

resultsThirty-three patients underwent radical hysterectomy with pelvic lymphadenectomy for cervical cancer treatment. The median age at diagnosis was 43 years. After surgery, 15 patients (45%) were dispositioned to surveillance and 18 (55%) were referred for adjuvant treatment with radiotherapy and/or chemotherapy. All patients had follow-up data available, with a median follow-up time of 19 months (range, 0.2 to 37.5). Only one patient died, and the overall survival is 95.7% (95% CI, 87.7% to 100%) at 12.7 months.

conclusionThe IGCS program has provided training to physicians at Maputo Central Hospital, resulting in surgery for cervical cancer being available to patients in Mozambique. This is an important step in the global elimination of cervical cancer.

Indexed as

GynecologyMedical OncologyUterine Cervical NeoplasmsAdultAgedFemaleHumansHysterectomyMiddle AgedMozambiqueRetrospective StudiesTreatment Outcome

Identifiers

PMID40499056
PMCPMC12179889

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.