SynthesisAnnals of plastic surgery2025
Encapsulation of Adipose-Derived Stem Cells in Collagen-Based Hydrogel: Regenerative Therapy for Burn Wound Healing.
Synthesis in Annals of plastic surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Preclinical evaluation of recombinant type III collagen-based contact lens rewetting drops.Frontiers in ophthalmology · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionSkin graft is still the major treatment for burn injuries, despite its high risk of visible scarring which raises concerns regarding aesthetics and patient quality of life. This study proposes the usage of adipose-derived stem cells encapsulated in type I collagen-based hydrogel as a promoter to enhance wound healing, replace skin, and perfect skin regeneration. One of the potential tools for reconstructive surgery, regenerative treatments, and aesthetic enhancements due to their safety, efficiency, and cost-effectiveness is adipose-derived stem cells.
methodsThis review study used a systematic review approach and adhered to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guideline, encompassing preparation, execution, and reporting phases.
resultsBased on the study result, adipose-derived stem cells had the potential as adjuvant therapy in the burn recovery process. Application of adipose-derived stem cells enhances tissue regeneration after burn injury by reducing inflammation, stimulating blood vessel growth, releasing growth factors, and developing into various cell types upon appropriate stimulation. To maximize its potential, this modality is constructed in a collagen-based hydrogel which allows greater cell retention and engraftment, regardless of the complex microenvironment of the wound. Topical administration applied as the wound dressing after the skin graft procedure shows great absorption by the body with optimum cell viability and minimum cell retention in a less invasive way.
conclusionsFurther studies regarding dosage and long-term side effects are required to obtain maximum usage of this stem cell therapy in the management of burn wound healing.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.