ReviewPLoS neglected tropical diseases2025
Glanders: An ancient and emergent disease with no vaccine or treatment on site.
Review in PLoS neglected tropical diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
6 citing papers in PubMed.
- Discovery of repurposed drugs that disrupt intracellular replication of Burkholderia pseudomallei and Burkholderia mallei and protect against lethal aerosol infection.PLoS pathogens · 2026Article
- Biosafety and biosecurity forClinical microbiology reviews · 2026Review
- Human infections caused by pathogenic Burkholderia: current clinical challenges and future perspectives.Infection · 2026Review
- Glanders: Past, Present and Future of a Neglected Zoonosis as a Threat in Veterinary and Human Health.Veterinary medicine and science · 2026Review
- Cutting edge reviews: Battling one Neglected Tropical Disease after another.PLoS neglected tropical diseases · 2026Article
- Glanders: Historical military use and potential bioterrorism concern.Open veterinary journal · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
Abstract
Glanders is a highly contagious and potentially fatal zoonotic disease that primarily affects equines but can also infect humans. Caused by the bacterium Burkholderia mallei, the disease is characterized by nodular lesions in the lungs and ulcerations of the skin and mucous membranes. This review explores the historical significance of glanders, from its early recognition to its role as a biothreat agent. Additionally, it examines the global distribution and epidemiology of glanders, emphasizing its status as a re-emerging disease in certain regions. Finally, the clinical presentation, diagnosis, and host-immunity responses to B. mallei infection are discussed, with a focus on the ongoing efforts to develop a viable vaccine.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.