Evidence map›Paper›PMID 40498704›Full record

ArticlePloS one2025

Epidemiology and clinical management of acute diarrhoea in dogs under primary veterinary care in the UK.

Dan G O'Neill, Lauren J Prisk, Dave C Brodbelt, David B Church, Fergus Allerton

Abstract read
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Article in PloS one, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Dan G O'NeillPathobiology and Population Sciences, The Royal Veterinary College, Hatfield, Herts, United Kingdom.ORCID https://orcid.org/0000-0003-1115-2723
Lauren J PriskPathobiology and Population Sciences, The Royal Veterinary College, Hatfield, Herts, United Kingdom.
Dave C BrodbeltPathobiology and Population Sciences, The Royal Veterinary College, Hatfield, Herts, United Kingdom.
David B ChurchClinical Sciences and Services, The Royal Veterinary College, Hatfield, Herts, United Kingdom.
Fergus AllertonWillows Veterinary Centre and Referral Service, Solihull, West Midlands, United Kingdom.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAcute diarrhoea is a common canine veterinary presentation in the UK. This study aimed to report the incidence, demographic risk factors and clinical management for acute diarrhoea diagnosed under primary veterinary care in the UK in 2019.

methodsA cohort study design with a cross-sectional analysis was applied to anonymised VetCompass clinical data. Risk factor analysis used multivariable logistic regression modelling.

resultsThe analysis included a random sample of 1,835 confirmed incident acute diarrhoea cases in 2019 from an overall study population of 2,250,417 dogs. After accounting for subsampling, the estimated one-year incidence risk for acute diarrhoea in dogs overall was 8.18% (95% CI: 7.83-8.55). Of the first acute diarrhoea event in 2019 for the 1,835 cases, 1473 (80.27%) had only one physical visit for veterinary care related to the acute diarrhoea. The most common comorbid clinical signs with acute diarrhoea included vomiting (n = 812, 44.25%), reduced appetite (508, 27.68%) and lethargy (444, 24.20%). Overall, 538 (29.32%) cases were recorded as haemorrhagic diarrhoea. The most common clinical managements were probiotics (n = 1094, 59.62%), dietary management (807, 43.98%), antibiosis (701, 38.20%) and maropitant (441, 24.03%). Six breeds showed increased odds of acute diarrhoea compared with crossbred dogs: Maltese (OR 2.17, 95% CI 1.25-3.77), Miniature Poodle (OR 2.17, 95% CI 1.19-3.95), Cavapoo (OR 2.07, 95% CI 1.32-3.25), German Shepherd Dog (OR 1.69, 95% CI 1.29-2.22), Yorkshire Terrier (OR 1.51, 95% CI 1.15-1.98) and Cockapoo (OR 1.36, 95% CI 1.05-1.74). The odds of diagnosis increased in dogs aged under 3 years and dogs aged over 9 years, compared to dogs aged 4-5 years.

conclusionsThis study confirms acute diarrhoea as a common clinical condition in dogs managed under primary veterinary care, with 1-in-12 dogs diagnosed each year. The identified breed predispositions suggest some genetic element to the condition. The clinical outcomes following veterinary care appear to be very positive, with over 80% of acute diarrhoea cases not receiving a second veterinary visit. However, antibiotic use remained frequent, despite years of recommendation to the contrary and raises concerns about unnecessary antibiotic therapy for this condition.

Indexed as

DiarrheaDog DiseasesAcute DiseaseAnimalsCohort StudiesCross-Sectional StudiesDogsFemaleIncidenceMaleProbioticsRisk FactorsUnited Kingdom

Identifiers

PMID40498704
PMCPMC12156985

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.