ArticleThe journals of gerontology. Series A, Biological sciences and medical sciences2025
Frailty and physical activity: are all physical activity variables equal?
Article in The journals of gerontology. Series A, Biological sciences and medical sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Relationship between 24-h movement behaviors and frailty-a scoping review.Frontiers in public health · 2026Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
backgroundFrailty, defined as diminished physiological and functional reserve, is linked to negative health outcomes such as falls, fractures, and disability. Physical activity dose plays a significant role in preventing and reducing physical frailty, but the influence of different PA variables on deficit accumulation (ie, frailty index [FI]) is not fully understood. Thus, we examined the relationship between physical activity variables and FI among older adults.
methodsWe utilized Round 11 (2021) data from the National Health and Aging Trends Study, a longitudinal study of Medicare beneficiaries aged 65 and older in the United States. Our participants included 726 community-dwelling older adults who had at least 3 valid days of accelerometer data and all data needed to calculate FI. Demographic variables, health conditions, and physical function were assessed through standardized interviews and objective assessments. We completed regression and Poisson models to estimate FI value and prevalence ratios for frailty.
resultsParticipants spent 339 daily minutes performing physical activity. The activity was accumulated over 88 bouts averaging 3.8 minutes. Those with frailty have lower levels of activity, higher levels of non-activity and sleep, higher activity fragmentation, fewer bouts, shorter bouts, and lower intensity over 10 consecutive minutes (ps < .001). After adjusting for all activity metrics, activity fragmentation (B = 1.32) and intensity of the most active 10-minute bout (B= -0.46) remained significantly associated with FI (P ≤ .04).
conclusionsLow-intensity and fragmented physical activity is linked to frailty. Further research should explore the role of sustained activity and fragmentation in monitoring and guiding interventions for frailty.
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