Evidence map›Paper›PMID 40498391›Full record

ArticleCanadian journal of public health = Revue canadienne de sante publique2026

Machine learning used to study risk factors for chronic diseases: A scoping review.

Mahek Shergill, Steve Durant, Sharon Birdi, Roxana Rabet, Carolyn Ziegler, Shehzad Ali, David Buckeridge, Marzyeh Ghassemi, Jennifer Gibson, Ava John-Baptiste and 10 more

Abstract readScoping Review
In one paragraph

Article in Canadian journal of public health = Revue canadienne de sante publique, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Mahek ShergillUpstream Lab, MAP Centre for Urban Health Solutions, Li Ka Shing Knowledge Institute, St. Michael's Hospital, Toronto, ON, Canada.
Steve DurantUpstream Lab, MAP Centre for Urban Health Solutions, Li Ka Shing Knowledge Institute, St. Michael's Hospital, Toronto, ON, Canada.
Sharon BirdiUpstream Lab, MAP Centre for Urban Health Solutions, Li Ka Shing Knowledge Institute, St. Michael's Hospital, Toronto, ON, Canada.
Roxana RabetUpstream Lab, MAP Centre for Urban Health Solutions, Li Ka Shing Knowledge Institute, St. Michael's Hospital, Toronto, ON, Canada.
Carolyn ZieglerHealth Science Library, Unity Health Toronto, Toronto, ON, Canada.
Shehzad AliDepartment of Epidemiology and Biostatistics, Western Centre for Public Health & Family Medicine, Western University, London, ON, Canada.
David BuckeridgeDepartment of Epidemiology, Biostatistics and Occupational Health, School of Population and Global Health, McGill University, Montreal, QC, Canada.
Marzyeh GhassemiDepartment of Electrical Engineering and Computer Science (EECS), Institute for Medical Engineering & Science (IMES), MIT, Cambridge, MA, USA.
Jennifer GibsonJoint Centre for Bioethics, University of Toronto, Toronto, ON, Canada.
Ava John-BaptisteDepartments of Epidemiology & Biostatistics, Anesthesia & Perioperative Medicine, Schulich Interfaculty Program in Public Health, Western University, London, ON, Canada.
Jillian MacklinUpstream Lab, MAP Centre for Urban Health Solutions, Li Ka Shing Knowledge Institute, St. Michael's Hospital, Toronto, ON, Canada.
Melissa McCraddenDepartment of Bioethics, The Hospital for Sick Children, Toronto, ON, Canada.
Kwame McKenzieWellesley Institute, Toronto, ON, Canada.
Parisa NaraeiDepartment of Computer Science, Toronto Metropolitan University, Toronto, ON, Canada.
Akwasi Owusu-BempahDepartment of Sociology, Faculty of Arts & Sciences, University of Toronto, Toronto, ON, Canada.
Laura C RosellaDivision of Clinical Public Health, Dalla Lana School of Public Health, University of Toronto, Toronto, ON, Canada.
James ShawDepartment of Physical Therapy, Faculty of Medicine, University of Toronto, Toronto, ON, Canada.
Ross UpshurJoint Centre for Bioethics, University of Toronto, Toronto, ON, Canada.
Sharmistha MishraDivision of Infectious Diseases, Department of Medicine, Faculty of Medicine, University of Toronto, Toronto, ON, Canada.
Andrew D PintoUpstream Lab, MAP Centre for Urban Health Solutions, Li Ka Shing Knowledge Institute, St. Michael's Hospital, Toronto, ON, Canada. andrew.pinto@utoronto.ca.

Funding

CIHR 460906
6 · The paper itself

Abstract

objectivesMachine learning (ML) has received significant attention for its potential to process and learn from vast amounts of data. Our aim was to perform a scoping review to identify studies that used ML to study risk factors for chronic diseases at a population level, notably those that incorporated methods to mitigate algorithmic bias. We focused on ML applications for the most common risk factors for chronic disease: tobacco use, alcohol use, unhealthy eating, physical activity, and psychological stress.

methodsWe searched the peer-reviewed, indexed literature using Medline (Ovid), Embase (Ovid), Cochrane Central Register of Controlled Trials and Cochrane Database of Systematic Reviews (Ovid), Scopus, ACM Digital Library, INSPEC, and Web of Science's Science Citation Index, Social Sciences Citation Index, and Emerging Sources Citation Index. Among the included studies, we examined whether bias was considered and identified strategies employed to mitigate bias. SYNTHESIS: The search identified 10,329 studies, and 20 met our inclusion criteria. The studies we identified used ML for a wide range of goals, from prediction of chronic disease development to automating the classification of data to identifying new associations between risk factors and disease. Nine studies (45%) included some discussion of algorithmic bias. Studies that incorporated a broad array of sociodemographic variables did so primarily to improve the performance of a ML model rather than to mitigate potential harms to populations made vulnerable by social and economic policies.

conclusionThis work contributes to our understanding of how ML can be used to advance population and public health.

Indexed as

Machine LearningChronic DiseaseHumansRisk FactorsArtificial intelligenceMachine learningNon-communicable diseasesPopulation healthPublic healthRisk factors

Identifiers

PMID40498391
PMCPMC12992777

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.