Evidence map›Paper›PMID 40498357›Full record

ArticleAnalytical and bioanalytical chemistry2025

Quantitative determination and validation of 96 pesticides in cannabis by LC-MS/MS and GC-MS/MS.

D A MacKenzie, A M Anyanwu, G McRae, J E Melanson

Abstract readValidation Study
In one paragraph

Article in Analytical and bioanalytical chemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Interpol review of forensic drug chemistry, 2022-2025.Forensic science international. Synergy · 2026
    Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

D A MacKenzieNational Research Council of Canada, Metrology, 1200 Montreal Road, Ottawa, ON, K1A0R6, Canada. Douglas.MacKenzie@nrc-cnrc.gc.ca.ORCID http://orcid.org/0000-0001-6182-1169
A M AnyanwuEnvironment and Climate Change Canada, Air Quality Research Division, 335 River Road, Ottawa, ON, K1V1C7, Canada.
G McRaeNational Research Council of Canada, Metrology, 1200 Montreal Road, Ottawa, ON, K1A0R6, Canada.
J E MelansonNational Research Council of Canada, Metrology, 1200 Montreal Road, Ottawa, ON, K1A0R6, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Canada has established a strict set of testing requirements for pesticides that are unauthorized for use on cannabis, currently holding the most extensive list of analytes in North America to date, listing minimum method performance limits rather than maximum allowable concentration limits. These requirements establish the need for validated analytical methods capable of quantifying pesticides and growth regulators in highly variable cannabis inflorescence prior to distribution and sale. We have developed quantitative LC-MS/MS and GC-MS/MS methods capable of quantifying the 96 pesticides unauthorized in Canada for use on cannabis in dried cannabis flower and hemp. Herein, we report the validation results for linearity, precision, within- and between-sample accuracy, recovery, ion suppression, and limits of quantitation in dried cannabis inflorescence. Accuracy is evaluated in 10 cultivars varying in major cannabinoid content as well as ground whole-plant hemp to demonstrate method performance over a range of sample types. Results of the application of the current method to six cannabis samples seized from illegal storefronts by the Ontario Provincial Police are also reported.

Indexed as

CannabisGas Chromatography-Mass SpectrometryPesticidesTandem Mass SpectrometryCanadaChromatography, LiquidLimit of DetectionLiquid Chromatography-Mass SpectrometryReproducibility of ResultsPesticidesCannabisGC-MS/MSLC-MS/MSPesticides

Identifiers

PMID40498357
PMCPMC12227361

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.