Evidence map›Paper›PMID 40498293›Full record

ArticleAMB Express2025

Ochratoxin A reduction in wine fermentation: evaluating the potential of Lachancea thermotolerans.

Javier Vicente, Daniel Vidal, Wendu Tesfaye, Fernando Calderón, Fernando García, Santiago Benito

Abstract read
In one paragraph

Article in AMB Express, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Microbial Detoxification of Ochratoxin A in Food.Foods (Basel, Switzerland) · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Javier VicenteDepartment of Genetics, Physiology and Microbiology. Unit of Microbiology. Biology Faculty, Complutense University of Madrid, 28040, Madrid, Spain.
Daniel VidalAgri-Food Arbitration Laboratory, Deputy Directorate General for Food Quality Control and Agri-Food Laboratories, Ministry of Agriculture, Fisheries and Food, 28023, Madrid, Spain.
Wendu TesfayeDepartment of Chemistry and Food Technology, Polytechnic University of Madrid, University City, 28040, Madrid, Spain.
Fernando CalderónDepartment of Chemistry and Food Technology, Polytechnic University of Madrid, University City, 28040, Madrid, Spain.
Fernando GarcíaAgri-Food Arbitration Laboratory, Deputy Directorate General for Food Quality Control and Agri-Food Laboratories, Ministry of Agriculture, Fisheries and Food, 28023, Madrid, Spain.
Santiago BenitoDepartment of Chemistry and Food Technology, Polytechnic University of Madrid, University City, 28040, Madrid, Spain. santiago.benito@upm.es.

Funding

Ministerio de Ciencia, Innovación y Universidades PID2020-119008RB-I00/AEI/10.13039/501100011033Universidad Complutense de Madrid CT58/21-CT59/21
6 · The paper itself

Abstract

Ochratoxin A is a mycotoxin commonly found in wine, primarily produced by fungal species from the Aspergillus and Penicillium genera. Due to its nephrotoxic, neurotoxic, immunotoxic, and carcinogenic properties, ochratoxin A contamination in wine is a significant concern for public health. This study investigates the potential of Lachancea thermotolerans in reducing ochratoxin A levels during wine fermentation, evaluating its fermentative performance and impact on key enological parameters. Fermentation trials with 32 L. thermotolerans strains demonstrated considerable variability in fermentation kinetics, ethanol production, and sugar consumption. The yeast exhibited strain-dependent variability in the production of organic acids, including succinic and lactic acid, leading to significant differences in total acidity and pH. Additionally, L. thermotolerans produced glycerol levels comparable to or exceeding those of Saccharomyces cerevisiae. The ability of L. thermotolerans to reduce ochratoxin A was highly strain-dependent, with reductions ranging widely. The most effective strains achieved ochratoxin A reductions exceeding those previously reported for S. cerevisiae. However, an inverse correlation was observed between ochratoxin A reduction and polyphenol retention, suggesting that strains with high ochratoxin A adsorption may also bind anthocyanins and polyphenols, affecting wine color and structure. These findings highlight L. thermotolerans as a promising non-Saccharomyces yeast for mitigating ochratoxin A contamination in wine while contributing positively to acidity modulation and sensory attributes. The study underscores the importance of strain selection to balance ochratoxin A detoxification with desirable enological properties, particularly in regions where contamination poses a significant challenge to wine safety and quality.

Indexed as

AcidityLachancea thermotoleransLactic acidOchratoxin AWine

Identifiers

PMID40498293
PMCPMC12158886

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.