Evidence map›Paper›PMID 40498265›Full record

ReviewCurrent oncology reports2025

Chronic Fatigue in Cancer Survivorship: Psychiatry Versus Oncology or Psychiatry with Oncology?

Vasilios Kafetzopoulos, Maria Pittaka, Georgios Ioannidis, Ivi Moniem

Abstract readReview
In one paragraph

Review in Current oncology reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Vasilios KafetzopoulosDepartment of Psychiatry, Medical School, University of Cyprus, Nicosia, Cyprus. kafetzopoulos.vasileios@ucy.ac.cy.ORCID https://orcid.org/0000-0002-3353-5242
Maria PittakaOncology Department, Nicosia General Hospital, State Health Services Organization, Nicosia, Cyprus.
Georgios IoannidisOncology Department, Nicosia General Hospital, State Health Services Organization, Nicosia, Cyprus.ORCID http://orcid.org/0000-0003-2535-7279
Ivi MoniemDepartment of Psychiatry, Medical School, University of Cyprus, Nicosia, Cyprus.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purpose of reviewCancer-related fatigue (CRF) is a prevalent and debilitating symptom among breast cancer survivors​ with a significant adverse impact on quality of life​. This comprehensive review synthesizes the current understanding of CRF's complex pathophysiology, including the interplay of inflammatory, neuroendocrine, and psychosocial mechanisms​, and evaluates diverse intervention strategies. RECENT

findingsNon-pharmacologic approaches (e.g., structured exercise, cognitive-behavioural therapy, mindfulness) have the strongest evidence for alleviating CRF and are emphasized as first-line treatments in oncology guidelines (e.g., ASCO, NCCN, ESMO). In contrast, pharmacologic options such as psychostimulants or bupropion show only modest benefits​, with mixed efficacy and notable side effects​, underscoring their limited role. Comparing oncology-focused guidelines with those for myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) which are psychiatry-focused highlight key differences in management approaches and the need for a unified, multidisciplinary framework across specialties. Modern multidisciplinary, individualized survivorship care, integrating oncologic, psychosocial, and rehabilitative strategies call for adoption of updated, integrated clinical guidelines to optimally address CRF​. By consolidating evidence and expert recommendations, this review aims to inform and enhance the clinical management of CRF and improve survivorship outcomes for breast cancer survivors.

Indexed as

Breast NeoplasmsCancer SurvivorsFatigueFatigue Syndrome, ChronicNeoplasmsFemaleHumansMedical OncologyPsychiatryQuality of LifeSurvivorshipCancer related fatigueGuidelinesMultidisciplinaryMyalgic encephalomyelitis/Chronic fatigue syndrome (ME/CFS)PsychiatrySurvivorship

Identifiers

PMID40498265
PMCPMC12328488

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.