Evidence map›Paper›PMID 40498126›Full record

ArticlePediatric surgery international2025

Prevalence and risk factors of feeding difficulties in children with delayed reconstruction of esophageal atresia: a Swedish nationwide study.

Sofie Örnö Ax, Elin Öst, Helene Engstrand Lilja, Erik Omling, Vladimir Gatzinsky, Jan F Svensson, Ann-Marie Kassa, Linus Jönsson, AnnaMaria Tollne, Pernilla Stenström and 2 more

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Article in Pediatric surgery international, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

12 authors.

Sofie Örnö AxInstitute of Clinical Sciences, Department of Pediatrics, Queen Silvia Children's Hospital, Rondvägen 10, 41640, Gothenburg, Sweden. sofie.orno.ax@gu.se.
Elin ÖstDepartment of Pediatric Surgery, Karolinska University Hospital, Stockholm, Sweden.
Helene Engstrand LiljaDepartment of Women's and Children's Health, Uppsala University, Uppsala, Sweden.
Erik OmlingDepartment of Pediatric Surgery, Lund University, Skane University Hospital, Lund, Sweden.
Vladimir GatzinskyInstitute of Clinical Sciences, Department of Pediatrics, Queen Silvia Children's Hospital, Rondvägen 10, 41640, Gothenburg, Sweden.
Jan F SvenssonDepartment of Pediatric Surgery, Karolinska University Hospital, Stockholm, Sweden.
Ann-Marie KassaDepartment of Women's and Children's Health, Uppsala University, Uppsala, Sweden.
Linus JönssonInstitute of Clinical Sciences, Department of Pediatrics, Queen Silvia Children's Hospital, Rondvägen 10, 41640, Gothenburg, Sweden.
AnnaMaria TollneDepartment of Pediatric Surgery, Karolinska University Hospital, Stockholm, Sweden.
Pernilla StenströmDepartment of Pediatric Surgery, Lund University, Skane University Hospital, Lund, Sweden.
Kate AbrahamssonInstitute of Clinical Sciences, Department of Pediatrics, Queen Silvia Children's Hospital, Rondvägen 10, 41640, Gothenburg, Sweden.
Michaela Dellenmark-BlomInstitute of Clinical Sciences, Department of Pediatrics, Queen Silvia Children's Hospital, Rondvägen 10, 41640, Gothenburg, Sweden.

Funding

ALF Grants from Region of Västra Götaland ALFGBG-942815; ALFGBG-964986HKH Kronprinsessan Lovisas förening för barnasjukvård/Stiftelsen Axel Tielmans Minnesfond 2021-00626The "Petter Silfverskiölds minnesfond" foundation 2021-292
6 · The paper itself

Abstract

purposeChildren with delayed reconstruction of esophageal atresia (DREA) have a high risk of morbidity. The aim of this study was to determine the prevalence of feeding difficulties in children with DREA, differences to children with primary anastomosis (PA) and identify risk factors for feeding difficulties in children with DREA.

methodsParents of 30 children with DREA, born 2001-2018, were recruited nationwide in Sweden and answered an author-developed screening survey about feeding difficulties. Outcomes were statistically compared to 105 children with PA, who were hypothesized to be more mildly affected Relative risk factors for feeding difficulties were investigated using negative binominal regression. Clinical data was retrieved from medical records. Level of significance p < 0.05.

resultsA majority of children with DREA (83%) had feeding difficulties, most commonly "longer mealtimes than peers" (73%) and "cough/choking during meals" (72%). Food infusion pump use (p = 0.043), need to avoid specific foods (p = 0.049) and need to eat with extra support by an adult (p < 0.0001) were more frequent than in PA. The relative risk of feeding difficulties increased with younger child age (p = 0.016), number of associated anomalies (p = 0.04) number of respiratory (p = 0.002) and digestive symptoms (p = 0.005).

conclusionFeeding difficulties in children with DREA are prevalent, underlining the need for multidisciplinary and targeted care early in life.

Indexed as

Esophageal AtresiaPostoperative ComplicationsAnastomosis, SurgicalChildChild, PreschoolFemaleHumansInfantInfant, NewbornMalePrevalenceRisk FactorsSwedenEsophageal atresiaFeedingMorbiditySurgical outcomes

Identifiers

PMID40498126
PMCPMC12159094

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