Evidence map›Paper›PMID 40497859›Full record

ReviewNanomaterials (Basel, Switzerland)2025

Application of NIR Fluorescent Materials in Imaging and Treatment of Tumors of Different Depths.

Mengdi Yu, Xuan Liu, Shuqiong Wang, Ziyao Qin, Beibei Hu, Zhiwei Li, Shiguo Sun

Erratum issuedAbstract readReview
In one paragraph

Review in Nanomaterials (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Mengdi YuCollege of Chemical and Pharmaceutical Engineering, Hebei University of Science and Technology, 26 Yuxiang Road, Shijiazhuang 050018, China.
Xuan LiuCollege of Chemical and Pharmaceutical Engineering, Hebei University of Science and Technology, 26 Yuxiang Road, Shijiazhuang 050018, China.
Shuqiong WangDepartment of Applied Chemistry, Hengshui University, 1088 Heping West Road, Hengshui 053000, China.
Ziyao QinCollege of Chemical and Pharmaceutical Engineering, Hebei University of Science and Technology, 26 Yuxiang Road, Shijiazhuang 050018, China.
Beibei HuCollege of Chemical and Pharmaceutical Engineering, Hebei University of Science and Technology, 26 Yuxiang Road, Shijiazhuang 050018, China.
Zhiwei LiCollege of Chemical and Pharmaceutical Engineering, Hebei University of Science and Technology, 26 Yuxiang Road, Shijiazhuang 050018, China.ORCID 0009-0007-9184-3298
Shiguo SunCollege of Chemical and Pharmaceutical Engineering, Hebei University of Science and Technology, 26 Yuxiang Road, Shijiazhuang 050018, China.

Funding

Hebei Research Center of Pharmaceutical and Chemical Engineering 225676121HHigher Education Teaching Reform Research and Practice Project of Hebei Province 2022GJJG186The State Key Laboratory Breeding Base-Hebei Province Key Laboratory of Molecular Chemistry for Drug No. 25
6 · The paper itself

Abstract

Deep-seated tumors present significant diagnostic challenges and pose substantial mortality risks due to their occult anatomical localization. Current diagnostic paradigms predominantly depend on conventional imaging modalities; nevertheless, inherent technical constraints persistently compromise diagnostic precision and therapeutic efficacy. In contrast to traditional methodologies, near-infrared (NIR; 700-1700 nm) fluorescence imaging (FLI) demonstrates superior sensitivity and spatiotemporal resolution, facilitating real-time intraoperative visualization and precision-guided surgical interventions. This paper explores fluorescence materials with tailored structures for tumors at different depths. We critically analyze optimization strategies for NIR fluorescence materials while evaluating their comparative advantages in stratified tissue imaging. This study presents a systematic evaluation of NIR fluorescence molecular tomography (FMT) systems and image reconstruction methodologies. These insights provide feasible ideas for detecting and treating tumors at varying depths in clinical practice. Furthermore, the application of NIR fluorescent materials in tumor diagnosis, navigation-guided surgery, and phototherapy (including photothermal, photodynamic, and immunomodulation therapies) is discussed. Finally, the prospects and challenges of clinical transformation are summarized.

Indexed as

fluorescence imaging (FLI)fluorescence molecular tomography (FMT)image-guided surgerynear-infrared (NIR)phototherapytumor

Identifiers

PMID40497859
PMCPMC12156901

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.