ReviewNanomaterials (Basel, Switzerland)2025
Surface Modification, Toxicity, and Applications of Carbon Dots to Cancer Theranosis: A Review.
Review in Nanomaterials (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
11 citing papers in PubMed.
- Review
- Reimagining Cannabidiol Delivery Through Carbon Nanodots.Molecules (Basel, Switzerland) · 2026Review
- Design, Synthesis, and Characterization ofACS omega · 2026Article
- Theranostic Rare-Earth-Doped Carbon Dots: An Effective Nanocarrier For Methotrexate Delivery in Colon Cancer.ACS omega · 2026Article
- Carbon Dots and Mitochondria-Advances in Targeting, Imaging, and Therapeutics.International journal of molecular sciences · 2026Review
- Carbon Dots and Biomimetic Membrane Systems: Mechanistic Interactions and Hybrid Nano-Lipid Platforms.Nanomaterials (Basel, Switzerland) · 2026Review
- Carbon Quantum Dots as Versatile Nanosystems for Biomedical Innovation: Mechanisms, Applications, and Translational Prospects.British journal of biomedical science · 2026Review
- Novel Carbon Dots Nanomaterials for the Precision Diagnosis and Treatment of Acute Lung Injury and Acute Respiratory Distress Syndrome: Mechanisms and Applications.International journal of nanomedicine · 2026Review
- Reproducibility roadblocks and standardization in carbon dot synthesis: a critical review of current practices, challenges, and future directions.Mikrochimica acta · 2025Review
- The Role of Carbon Dots in Regulating the Periodontal Immune Microenvironment: Progress and Perspectives.International journal of molecular sciences · 2025Review
- Green carbon dots in the era of AI: sustainable synthesis, intelligent drug delivery, advanced diagnostics, and bioimaging.Turkish journal of biology = Turk biyoloji dergisi · 2025Review
Corrections and comments
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Authors and funding
9 authors.
Funding
Abstract
Cancer remains one of the leading causes of death worldwide, prompting extensive research into novel theranostic (combined word of diagnostic and therapeutic) strategies. Nanomedicine has emerged as a potential breakthrough in cancer theranosis, overcoming limitations of conventional approaches. Among such approaches, carbon dots (CDs) with a size smaller than 10 nm have garnered significant attention for their potential use in cancer theranosis, owing to their low toxicity, good water solubility, easy synthesis, facile surface modification, and unique optical and photothermal and photodynamic properties. Researchers have demonstrated that surface functionalization of CDs with diverse hydrophilic groups can be easily achieved by choosing proper carbon precursors in synthesis, and further surface modification of CDs with cancer-targeting ligands, photosensitizers, anticancer drugs, and genes can also be easily achieved using various methods, thereby establishing a versatile approach for cancer theranosis. This review described the various surface modification methods of CDs, in vitro and in vivo toxicity of CDs, and various cancer theranostic methods such as drug delivery, photodynamic therapy, photothermal therapy, gene therapy, sonodynamic therapy, and gas therapy. Therefore, CDs can serve as various mono and combined theranostic modalities, offering us new methods for cancer theranosis.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.