Evidence map›Paper›PMID 40497654›Full record

ArticleThe Laryngoscope2025

Robotic-Assisted Electrode Array Insertion Improves Rates of Hearing Preservation.

Uzair A Khan, Camille C Dunn, Rachel A Scheperle, Jacob Oleson, Alexander D Claussen, Bruce J Gantz, Marlan R Hansen

Abstract read
In one paragraph

Article in The Laryngoscope, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Uzair A KhanDepartment of Otolaryngology - Head and Neck Surgery, University of Iowa Health Care, Iowa City, Iowa, USA.
Camille C DunnDepartment of Otolaryngology - Head and Neck Surgery, University of Iowa Health Care, Iowa City, Iowa, USA.ORCID 0000-0001-7839-2073
Rachel A ScheperleDepartment of Otolaryngology - Head and Neck Surgery, University of Iowa Health Care, Iowa City, Iowa, USA.ORCID 0000-0002-0285-526X
Jacob OlesonDepartment of Biostatistics, University of Iowa, Iowa City, Iowa, USA.
Alexander D ClaussenDepartment of Otolaryngology - Head and Neck Surgery, University of Iowa Health Care, Iowa City, Iowa, USA.ORCID 0000-0003-3056-5646
Bruce J GantzDepartment of Otolaryngology - Head and Neck Surgery, University of Iowa Health Care, Iowa City, Iowa, USA.
Marlan R HansenDepartment of Otolaryngology - Head and Neck Surgery, University of Iowa Health Care, Iowa City, Iowa, USA.ORCID 0000-0002-6884-4897

Funding

Speech Production &LanguageP50DC000242 · NIDCD · UNIVERSITY OF IOWA · PI Inyong Choi · 1989 to 2026
$58.8M
Research Training Program in OtolaryngologyT32DC000040 · NIDCD · UNIVERSITY OF IOWA · PI HANSEN, MARLAN R · 1993 to 2025
$5.4M
NIDCD NIH HHS P50 DC000242NIDCD NIH HHS T32 DC000040NIH HHS NIH NIDCD P50-DC000242NIH HHS NIH NIDCD T32-DC000040-29
6 · The paper itself

Abstract

OBJECTIVE(S): Robotic-assisted electrode array (EA) insertion is a promising technique that may enhance hearing preservation in cochlear implant (CI) surgery. The purpose of our study is to understand the extent to which robotic-assisted EA insertion improves hearing preservation.

methodsTwenty-four adult patients underwent CI surgery with manual EA insertion and 27 adult patients underwent CI surgery with robotic-assisted EA insertion using the iotaSOFT system. The EAs used included the Flex 20/24/26. The primary outcome variable was low frequency pure-tone average (LFPTA), defined as mean audiometric threshold at 125, 250, and 500 Hz. This was measured preoperatively, at initial activation (within 4 weeks of surgery), and subsequently at 2 weeks, 3 months, 6 months, and 1 year. Functional acoustic hearing was defined as LFPTA < 80 dB HL.

resultsSeventeen out of 24 patients (71%) in the manual insertion group and 23 out of 27 patients (85%) in the robotic-assisted EA insertion group had preserved functional acoustic hearing (< 80 dB HL) up till 1 year (Fisher's exact test (two-tailed) is not statistically significant, p = 0.31). The number needed to treat with robotic-assisted EA insertion to prevent one additional negative outcome of loss of functional acoustic hearing would be 7 (1/0.14).

conclusionRobotic-assisted EA insertion is associated with improved hearing preservation over 1 year compared with manual insertion. Hearing preservation leads to improved outcomes and therefore every effort should be made to preserve the delicate structure and function of the cochlea during EA insertion. Robotic-assisted EA insertion advances that objective. LEVEL OF EVIDENCE: III (cohort study).

Indexed as

Cochlear ImplantationCochlear ImplantsElectrodes, ImplantedHearingHearing LossRobotic Surgical ProceduresAdultAgedAudiometry, Pure-ToneFemaleHumansMaleMiddle AgedTreatment Outcomecochlear implanthearing preservationrobotic‐assisted insertion

Identifiers

PMID40497654
PMCPMC12576857

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.