Evidence map›Paper›PMID 40497555›Full record

ArticleJournal of animal science2025

Hydrolyzed chicken liver and increasing crude protein levels on palatability, digestibility, and intestinal fermentation products of cats.

Pamela Prestes Sezerotto, Caroline Fredrich Dourado Pinto, Ariane Miranda da Silva, Joyce Cristina Paiva Francisco, Marcelino Bortolo, Fábio Ritter Marx, Ricardo de Souza Vasconcellos, Luciano Trevizan

Abstract read
In one paragraph

Article in Journal of animal science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Pamela Prestes SezerottoAnimal Science Departament, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil.
Caroline Fredrich Dourado PintoSouth America Jr. R&D Scientist, Nutrisurance Division, Kemin Industries, Inc., Vargeão, Brazil.ORCID 0000-0002-3531-3985
Ariane Miranda da SilvaAnimal Science Departament, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil.
Joyce Cristina Paiva FranciscoAnimal Science Departament, Universidade Estadual de Maringá, Maringá, Brazil.
Marcelino BortoloSouth America Senior R&D Manager, Nutrisurance Division, Kemin Industries, Inc., Indaiatuba, Brazil.
Fábio Ritter MarxNorth America Senior R&D Manager, Nutrisurance Division, Kemin Industries, Inc., Des Moines, IA, USA.
Ricardo de Souza VasconcellosAnimal Science Departament, Universidade Estadual de Maringá, Maringá, Brazil.ORCID 0000-0002-0333-4300
Luciano TrevizanAnimal Science Departament, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil.ORCID 0000-0002-1819-0653

Funding

Kemin Nutrisurance, the pet food and rendering technologies division of Kemin Industries, Inc.
6 · The paper itself

Abstract

Feeding companion cats with diets based on hydrolyzed proteins may improve palatability and digestibility due to the presence of peptides and free amino acids. Furthermore, using highly digestible protein sources can decrease the undigested protein content that reaches the hindgut, thereby modifying fermentation end metabolites. This study aimed to evaluate the effects of replacing poultry byproduct meal (PBM), as the most traditional protein source for cats, with hydrolyzed chicken liver (HCL) added at 24%, 32%, and 40% of crude protein (CP) in the diet, replacing carbohydrates from brewers rice. The combination between 2 ingredients and 3 inclusions of CP permitted to test 6 extruded diets: PBM24, PBM32, PBM40; HCL24, HCL32, and HCL40. Thirty-six adult cats were arranged in a complete randomized block design to evaluate the apparent total tract digestibility (ATTD) of nutrients and energy, fermentative end products, and palatability. Crude protein ATTD increased at higher protein concentrations (P = 0.036). Fat ATTD was lower in cats fed HCL40 (P = 0.046). Carbohydrate digestibility decreased with high protein intake (P < 0.05) as a result of replacing carbohydrates with protein in the experimental diets. Gross energy ATTD was lower in cats fed HCL32 (P = 0.027). Similarly, cats fed HCL and HCL32 had lower metabolizable energy (P < 0.05) when compared to PBM. Fecal dry matter (P = 0.005) and fecal scores (P = 0.014) were lower with the inclusion of HCL (P < 0.05). Also, cats fed HCL32 had looser stools (2.61 out of a 0 to 5 score; P = 0.025), but within the acceptable range, compared to the other diets. Urinary pH increased with HCL inclusion and at higher protein concentrations (P < 0.05). Fecal acetate, propionate, valerate, total short-chain fatty acids (SCFA), isovalerate, and total volatile fatty acids (VFA) were higher in cats fed HCL compared to those fed PBM (P < 0.05). In the palatability test, cats mostly preferred diets based on HCL and with higher protein concentrations, mainly HCL40, over those based on PBM (Power test >0.75). The replacement of PBM by HCL in diets was highly accepted and improved the fermentative end metabolites associated with intestinal functionality in cats, especially SCFA.

Indexed as

Animal FeedDietary ProteinsDigestionLiverAnimal Nutritional Physiological PhenomenaAnimalsCatsChickensDietFemaleFermentationMaleDietary Proteinsextruded dietfelineprotein hydrolysateprotein levelshort-chain fatty acid

Identifiers

PMID40497555
PMCPMC12199764

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.