Evidence map›Paper›PMID 40497430›Full record

SynthesisAnnals of medicine2025

The performance of artificial intelligence in image-based prediction of hematoma enlargement: a systematic review and meta-analysis.

Wenjing Fan, Zhiping Wu, Wangyang Zhao, Luzhu Jia, Shuze Li, Wei Wei, Xin Chen

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in Annals of medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Wenjing FanDepartment of Epidemiology, School of Public Health, Dalian Medical University, Dalian, Liaoning, China.
Zhiping WuExperimental Teaching Center of Public Health, School of Public Health, Dalian Medical University, Dalian, Liaoning, China.
Wangyang ZhaoDepartment of Epidemiology, School of Public Health, Dalian Medical University, Dalian, Liaoning, China.
Luzhu JiaDepartment of Epidemiology, School of Public Health, Dalian Medical University, Dalian, Liaoning, China.
Shuze LiDepartment of Epidemiology, School of Public Health, Dalian Medical University, Dalian, Liaoning, China.
Wei WeiDepartment of Neurosurgery, Central hospital of Dalian University of Technology, Dalian, Liaoning, China.
Xin ChenDepartment of Epidemiology, School of Public Health, Dalian Medical University, Dalian, Liaoning, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAccurately predicting hematoma enlargement (HE) is crucial for improving the prognosis of patients with cerebral haemorrhage. Artificial intelligence (AI) is a potentially reliable assistant for medical image recognition. This study systematically reviews medical imaging articles on the predictive performance of AI in HE. MATERIALS AND

methodsRetrieved relevant studies published before October, 2024 from Embase, Institute of Electrical and Electronics Engineers (IEEE), PubMed, Web of Science, and Cochrane Library databases. The diagnostic test of predicting hematoma enlargement based on CT image training artificial intelligence model, and reported 2 × 2 contingency tables or provided sensitivity (SE) and specificity (SP) for calculation. Two reviewers independently screened the retrieved citations and extracted data. The methodological quality of studies was assessed using the QUADAS-AI, and Preferred Reporting Items for Systematic reviews and Meta-Analyses was used to ensure standardised reporting of studies. Subgroup analysis was performed based on sample size, risk of bias, year of publication, ratio of training set to test set, and number of centres involved.

results36 articles were included in this Systematic review to qualitative analysis, of which 23 have sufficient information for further quantitative analysis. Among these articles, there are a total of 7 articles used deep learning (DL) and 16 articles used machine learning (ML). The comprehensive SE and SP of ML are 78% (95% CI: 69-85%) and 85% (78-90%), respectively, while the AUC is 0.89 (0.86-0.91). The SE and SP of DL was 87% (95% CI: 80-92%) and 75% (67-81%), respectively, with an AUC of 0.88 (0.85-0.91). The subgroup analysis found that when the ratio of the training set to the test set is 7:3, the sensitivity is 0.77(0.62-0.91),

conclusionsArtificial intelligence algorithms based on imaging have shown good performance in predicting HE.

Indexed as

Artificial IntelligenceCerebral HemorrhageHematomaHumansPrognosisSensitivity and SpecificityTomography, X-Ray ComputedArtificial intelligencehematoma expansionintracerebral hematomamedical imagingmeta-analysis

Identifiers

PMID40497430
PMCPMC12160331

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.