Evidence map›Paper›PMID 40497258›Full record

ReviewFrontiers in allergy2025

Utility of tryptase genotyping in the screening, diagnosis, and management of systemic mastocytosis.

Jeremy C McMurray, Brandon J Schornack, Joaquin Villar, Tracy I George, Nathan A Boggs

Abstract readReview
In one paragraph

Review in Frontiers in allergy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jeremy C McMurrayAllergy & Immunology Service, Walter Reed National Military Medical Center, Bethesda, MD, United States.
Brandon J SchornackAllergy & Immunology Service, Walter Reed National Military Medical Center, Bethesda, MD, United States.
Joaquin VillarHenry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, United States.
Tracy I GeorgeARUP Laboratories and Huntsman Cancer Institute, Department of Pathology, University of Utah, Salt Lake, UT, United States.
Nathan A BoggsAllergy & Immunology Service, Walter Reed National Military Medical Center, Bethesda, MD, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tryptase genotyping has an expanding role in the screening, diagnosis, and management of patients with systemic mastocytosis (SM). Reference ranges for basal serum tryptase (BST) based on increased

Indexed as

basal serum tryptase (BST)hereditary alpha tryptasemiasystemic mastocytosis (SM)tryptase genotypingtyrosine kinase inhibitors (TKIs)

Identifiers

PMID40497258
PMCPMC12149127

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.