ArticleCirculation reports2025
The Relationship Between Health-Related Quality of Life and Frailty in Older Patients Participating in Early Phase II Cardiac Rehabilitation.
Article in Circulation reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
4 citing papers in PubMed.
- Evaluation of Exercise Tolerance in Cancer Patients With Cardiovascular Complications: A Japanese Single-Center Retrospective Study Using Cardiopulmonary Exercise Testing.Circulation reports · 2026Article
- Rehabilitation for Cardiorenal Multimorbidity: Epidemiology, Functional Phenotypes, and Effects on Physical Function, Renal Trajectory, and Prognosis.Journal of clinical medicine · 2026Review
- Differential increase in peak oxygen uptake with cardiac rehabilitation among patients with stage B versus C heart failure.European journal of physical and rehabilitation medicine · 2026Observational
- Cardiac Rehabilitation and Heart Failure With Preserved Ejection Fraction.Circulation reports · 2025Article
Corrections and comments
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Authors and funding
15 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Frailty is a significant prognostic risk factor for cardiovascular disease and it can lead to poor quality of life due to malnutrition, fatigue, and reduced physical activity. However, few studies have investigated how frailty affects older patients participating in cardiac rehabilitation (CR) on health-related quality of life (HRQoL). Methods and Results: Between November 2015 and December 2016 at Juntendo University Hospital, 217 patients (mean age 74.6±5.8 years; males 67%) participated in CR. Patients completed self-evaluations using the 36-item Short Form Survey (SF-36) and the Kihon Checklist (KCL) at the baseline of CR. The patients were divided into 3 groups: frailty group (n=81; 37%); pre-frailty group (n=71; 33%); and non-frailty group (n=65; 30%). Based on the KCL findings, we compared demographics, clinical measures, and SF-36 scores among the 3 groups. Sex, body mass index, 6-min walking distance, hemoglobin level, and low-density lipoprotein cholesterol differed significantly among the 3 groups. All SF-36 items also showed significant group differences; the frailty group scored lower than the other 2 groups on the physical component summary and mental component summary (MCS). Furthermore, the frailty group had a lower MCS score than the average Japanese age level. Conclusions: Frail older patients undergoing CR experience significant deterioration in both physical and mental dimensions of HRQoL.
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