Evidence map›Paper›PMID 40497027›Full record

ArticleFrontiers in nutrition2025

Effect of perioperative ONS combined with intestinal microecology in patients with colorectal cancer: a randomized clinical trial.

Xuanjun Liu, Weixu Mao, Guowei Zhao, Juan Liao, Qigang Li, Gan He

Abstract read
In one paragraph

Article in Frontiers in nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Xuanjun Liu *Department of Gastrointestinal Surgery, Yongchuan Hospital of Chongqing Medical University, Chongqing, China.
Weixu Mao *Department of Respiratory Medicine, The Affiliated Yongchuan District Traditional Chinese Medicine Hospital of Chongqing Medical University, Chongqing, China.
Guowei ZhaoDepartment of Gastrointestinal Surgery, Yongchuan Hospital of Chongqing Medical University, Chongqing, China.
Juan LiaoCentral Laboratory, Yongchuan Hospital of Chongqing Medical University, Chongqing, China.
Qigang LiDepartment of Gastrointestinal Surgery, Yongchuan Hospital of Chongqing Medical University, Chongqing, China.
Gan HeDepartment of Gastrointestinal Surgery, Yongchuan Hospital of Chongqing Medical University, Chongqing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: To investigate the combined effects of oral nutritional supplement (ONS) and intestinal microecology on postoperative nutrition status, inflammatory response and intestinal flora regulation colorectal cancer (CRC) patients. Methods: This prospective single-center randomized controlled trial (RCT) was conducted at Chongqing Yongchuan Hospital between December 2023 and December 2024. CRC patients were randomly assigned to one of two groups: a control group receiving ONS (55.8 g per dose, three times daily) or a test group receiving ONS (55.8 g per dose, three times daily) combined with bifidobacteria (1.5 g per dose, three times daily). Results: A total of 62 patients who undergoing radical colorectal cancer resection were enrolled. Participants were equally randomized into control and test groups ( Conclusion: Perioperative ONS combined with intestinal microbiota interventions improves postoperative nutritional status, modulates inflammatory dynamics, and accelerates intestinal function recovery. However, these interventions show limited impact on hospitalization duration and complication rates.

Indexed as

colorectal cancerintestinal microecologyoral nutritional supplementsperioperative periodpostoperative recovery

Identifiers

PMID40497027
PMCPMC12148894

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.