ArticlePublic health challenges2023
Factors influencing treatment adherence in paracoccidioidomycosis in Brazil.
Article in Public health challenges, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Factors influencing treatment adherence in paracoccidioidomycosis in Brazil.Public health challenges · 2023Article
- Rare clinical presentations of paracoccidioidomycosis: Epidemiological, clinical, and microbiological insights from a Brazilian reference center.The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious DiseasesArticle
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Authors and funding
8 authors.
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Abstract
Introduction: Paracoccidioidomycosis is a systemic mycosis endemic to Latin America, with frequent reports of poor treatment adherence resulting in worse clinical outcomes. The present study evaluated factors related to treatment adherence in patients with paracoccidioidomycosis. Methods: This cross-sectional study included data from medical records of patients with paracoccidioidomycosis treated between 2005 and 2018 in a reference hospital in southeastern Brazil. Clinical variables, demographic characteristics, and smoking and alcohol consumption were collected and analyzed. Results: Of the 198 cases included, most were adults (median age = 51 years), males (93.4%), presented chronic paracoccidioidomycosis (83.8%), reported smoking (90.4%) and alcohol consumption (84.8%), and 56.6% adhered to treatment. Treatment adherence was associated with the discontinuation of alcohol consumption (odds ratios (OR) = 5.227; 95% confidence interval (CI) = 2.697-10.129) and smoking (OR = 3.365; 95% CI = 1.781-6.358) during therapy. Conclusions: Patients' continued consumption of alcohol and tobacco was associated with non-adherence to treatment, suggesting that a joint therapeutic approach that addresses alcohol and tobacco use alongside paracoccidioidomycosis treatment may hold promise for improving adherence and patients' quality of life.
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