Evidence map›Paper›PMID 40496925›Full record

ArticleFrontiers in toxicology2025

Repetitive ozone exposure worsens features of muco-inflammatory disease in developed

Thao Vo, Sonika Patial, Yogesh Saini

Abstract read
In one paragraph

Article in Frontiers in toxicology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Single-cell transcriptomics reveal alveolar macrophage-specific responses in single-hit ozone exposure model in mice.American journal of physiology. Lung cellular and molecular physiology · 2026
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Thao VoDepartment of Population Health and Pathobiology, College of Veterinary Medicine, North Carolina State University, Raleigh, United States.
Sonika PatialDivision of translational Toxicology, National Institute of Environmental Health Sciences, Research Triangle Park, Durham, United States.
Yogesh SainiDepartment of Population Health and Pathobiology, College of Veterinary Medicine, North Carolina State University, Raleigh, United States.

Funding

Understanding the role of myeloid cells in ozone-induced airway diseaseR01ES030125 · NIEHS · NORTH CAROLINA STATE UNIVERSITY RALEIGH · PI SAINI, YOGESH · 2019 to 2024
$2.7M
Targeting Type-2 mucoinflammatory axis during the resolution of allergic lung inflammationR01ES035439 · NIEHS · NORTH CAROLINA STATE UNIVERSITY RALEIGH · PI Yogesh Saini · 2024 to 2026
$1.7M
Pathogenesis of mucous cell metaplasia in ozone-exposed airwaysR21ES034509 · NIEHS · NORTH CAROLINA STATE UNIVERSITY RALEIGH · PI SAINI, YOGESH · 2023 to 2024
$403k
NIEHS NIH HHS R01 ES030125NIEHS NIH HHS R01 ES035439NIEHS NIH HHS R21 ES034509
6 · The paper itself

Abstract

Introduction: Ambient exposure to ozone (O Methods: We exposed 3-week-old wild-type (WT) and Tg+ mice to either filtered air (FA) or 0.8 ppm O Results: As compared to FA-exposed WT mice, O Discussion: Together, our data using Tg+ mice with developed lungs exhibited several findings consistent with previous findings observed in Tg+ neonates. Interestingly, however, as opposed to the previous report in O

Indexed as

inflammationlungmiceozoneScnn1b-Tg+

Identifiers

PMID40496925
PMCPMC12148915

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.