Evidence map›Paper›PMID 40496917›Full record

ReviewFrontiers in veterinary science2025

Rumen acidosis in ruminants: a review of the effects of high-concentrate diets and the potential modulatory role of rumen foam.

Jinju Mao, Lizhi Wang

Abstract readReview
In one paragraph

Review in Frontiers in veterinary science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Review
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Genomic and phenotypic analysis ofFrontiers in microbiology · 2026
    Article
  15. Article
  16. Review
  17. Effects ofAnimals : an open access journal from MDPI · 2025
    Article
  18. Article
  19. The Effects of FermentingAnimals : an open access journal from MDPI · 2025
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Jinju MaoAnimal Nutrition Institute, Sichuan Agricultural University, Chengdu, China.
Lizhi WangAnimal Nutrition Institute, Sichuan Agricultural University, Chengdu, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This review delves into the intricate processes by which high concentrate diets (HCD) in ruminants trigger rumen acidosis, with particular attention to the initiating factors of the condition and the pivotal role of rumen foams in its progression. High concentrate diets lead to an excessive accumulation of acids within the rumen, creating a favorable environment for the formation of rumen foam. This foam exacerbates the severity of rumen acidosis, making it a more challenging condition to manage. Additionally, HCD significantly diminishes salivary secretion, which not only increases the viscosity of rumen contents but also hampers the absorption of volatile fatty acids and the release of carbon dioxide (CO₂). Moreover, the review highlights a previously underexplored mechanism: the build-up of CO₂ may play a crucial role in the pathogenesis of rumen acidosis. This oversight could have significant implications for understanding the onset and advancement of the condition. In essence, this paper seeks to establish a robust scientific framework to optimize ruminant nutrition and production practices, ultimately ensuring the health and well-being of these animals.

Indexed as

carbon dioxidepHrumen acidosisrumen foamsalivavolatile fatty acids

Identifiers

PMID40496917
PMCPMC12148896

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.