ArticleFrontiers in immunology2025
Telitacicept as double-targeted therapy for myasthenia gravis coexisting with connective tissue disease: three case reports.
Article in Frontiers in immunology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Telitacicept in myasthenia gravis: a systematic review of clinical outcomes, steroid-sparing effects, and safety.Frontiers in neurology · 2026Pooled it
- Triple immunotherapy containing telitacicept for systemic lupus erythematosus complicated by multiple autoimmune diseases: a case report.Frontiers in immunology · 2026Article
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Authors and funding
3 authors.
Funding
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Abstract
Myasthenia gravis (MG) and connective tissue diseases (CTD) are both B-cell-mediated, antibody-associated autoimmune diseases that share similar mechanisms of immune dysfunction. The coexistence of MG and CTD is a rare phenomenon, and its management remains challenging. Here, we report three cases of coexisting MG and CTD-specifically systemic lupus erythematosus and Sjögren's syndrome, and all three patients presented significant improvement 4 weeks after initiation of treatment with telitacicept. Minimal symptom expression (MSE) was achieved after 4, 6, and 7 weeks of treatment with telitacicept, for patients one-to-three, respectively. This therapy also enabled a reduction in prednisone dosage, with clinical symptoms of CTD remaining well controlled. These findings present preliminary evidence supporting Telitacicept as an effective treatment and a double-target therapy for the management of MG-CTD.
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