Evidence map›Paper›PMID 40496824›Full record

ArticleFrontiers in psychiatry2025

A mixed methods pilot feasibility study of the unified protocol group psychotherapy for early bipolar disorder.

Magnus Johan Engen, Siv Hege Lyngstad, Erlend Eikenæs, Jon Vøllestad, Margrethe Collier Høegh, Trine Vik Lagerberg, Sofie Ragnhild Aminoff

Abstract read
In one paragraph

Article in Frontiers in psychiatry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Magnus Johan EngenNydalen District Psychiatric Center, Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway.
Siv Hege LyngstadNydalen District Psychiatric Center, Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway.
Erlend EikenæsNydalen District Psychiatric Center, Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway.
Jon VøllestadDepartment of Clinical Psychology, Faculty of Psychology, University of Bergen, Bergen, Vestland, Norway.
Margrethe Collier HøeghSection for Psychosis Research, Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway.
Trine Vik LagerbergDepartment of Research and Development, Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway.
Sofie Ragnhild AminoffEarly Intervention in Psychosis Advisory Unit for South East Norway, Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this pilot study we explored the feasibility and acceptability of "The Unified Protocol for Transdiagnostic Treatment of Emotional Disorders" (UP) in a group format for individuals with early bipolar disorder (BD). Using a mixed methods design we integrated quantitative assessments and qualitative interviews to examine the practical application of UP in a clinical setting with a focus on how participants experienced the treatment. Nine participants with BD diagnoses completed the 12-session group intervention with modules focusing on emotion regulation through skills in non-judgmental awareness, cognitive flexibility, and exposure strategies. Quantitative findings indicated significant improvements in affective lability, overall functioning, and well-being. Qualitative findings highlighted participants' appreciation for the structured format and peer support from the group, which facilitated exploration of emotional experiences and skills practice. Participants reported particular benefit from non-judgmental awareness exercises, notably the "three-point check," and valued the group's role in reducing isolation and promoting shared learning. The study underscores UP's potential adaptability for individuals with BD in a group format. Possible adjustments are discussed, such as strengthening the focus on affective symptoms as well as increasing session duration and customizing exposure exercises for BD-specific challenges. Overall, the UP group format shows promise as a feasible, acceptable, and potentially effective adjunct treatment for BD, with room for targeted refinements to optimize outcomes.

Indexed as

affect regulationbipolar disorderemotion regulationfeasibility & acceptabilitymixed methodsunified protocol (UP)

Identifiers

PMID40496824
PMCPMC12149416

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.