Evidence map›Paper›PMID 40496799›Full record

ArticlePublic health challenges2023

Marburg virus outbreak in Tanzania: A threat to global health security.

Majani Edward, Godfred Yawson Scott, Withness John, Martha Ernest Rajabu, Elton Mahulu, Shuaibu Saidu Musa, Lucero-Prisno Iii Don Eliseo

Abstract read
In one paragraph

Article in Public health challenges, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Marburg Virus Disease: A Narrative Review.Health science reports · 2025
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Majani EdwardFaculty of Medicine St. Francis University College of Health and Allied Sciences Morogoro Tanzania.ORCID https://orcid.org/0000-0002-1671-9584
Godfred Yawson ScottDepartment of Medical Diagnostics Kwame Nkrumah University of Science and Technology Kumasi Ghana.ORCID https://orcid.org/0000-0001-7531-4213
Withness JohnFaculty of Medicine St. Francis University College of Health and Allied Sciences Morogoro Tanzania.
Martha Ernest RajabuFaculty of Medicine St. Francis University College of Health and Allied Sciences Morogoro Tanzania.
Elton MahuluFaculty of Medicine St. Francis University College of Health and Allied Sciences Morogoro Tanzania.
Shuaibu Saidu MusaDepartment of Nursing Science Ahmadu Bello University Zaria Nigeria.ORCID https://orcid.org/0000-0003-0138-3261
Lucero-Prisno Iii Don EliseoDepartment of Global Health and Development London School of Hygiene and Tropical Medicine London UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The current Marburg virus (MARV) outbreak in Tanzania served as a stark reminder of the ongoing threat posed by emerging infectious diseases and the urgent need for global health security. The Tanzanian Ministry of Health (MoH) officially declared the outbreak on March 21, 2023. Eight cases in all, five of which included fatalities, have been reported in the country at present. The virus is a member of the Filoviridae family closely related to the widely known Ebola virus. Similar to other filoviruses, MARV causes acute and lethal hemorrhagic fever in both human and nonhuman primates with high case fatality rates ranging from 24% to 90%. The outbreak has highlighted the need for improved disease surveillance and response systems, as well as increased funding for research into emerging infectious diseases. The Tanzanian MoH has deployed a response team to investigate and monitor the transmission in the Kagera Region. The team works closely in collaboration with other organizations, such as the World Health Organization and the Africa Centre for Disease Control and Prevention, to ensure the effective control of the situation. Although there is no vaccine or treatment approved for Marburg virus disease (MVD), supportive management improves survival. Existing infection prevention and control protocols for Ebola and other viral hemorrhagic fevers such as isolation and use of appropriate personal protective equipment can be used to prevent transmission of MVD. The global community must work together to strengthen health systems, enhance research efforts, and build resilient and responsive health systems to prevent future outbreaks of this kind. In this article, we have analyzed the MVD outbreak in Tanzania, specifically in the Bukoba district of the Kagera Region, and provided recommendations for the management of the current outbreak and future outbreaks.

Indexed as

disease outbreakglobal health securityinfection controlMarburg virus diseasepublic healthviral hemorrhagic fever

Identifiers

PMID40496799
PMCPMC12039743

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.